Protein Alignment GstE12 and MARS1

DIOPT Version :10

• Sequence 1: NP_611964.1
• Gene: GstE12 / 37960
• FlyBaseID: FBgn0027590
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_004981.2
• Gene: MARS1 / 4141
• HGNCID: 6898
• Length: 900
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 41/207 - (19%)
• Similarity: 71/207 - (34%)
• Gaps: 63/207 - (30%)

  Fly    55 IPTL-IDGEATIIDSHAICAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFARLRFLYEP 118
            :|.| :|....:..:.|||.|.....|.::..|..:.|...|              ..|:.....
Human    48 VPVLQLDSGNYLFSTSAICRYFFLLSGWEQDDLTNQWLEWEA--------------TELQPALSA 98

  Fly   119 ILYY-------GSTDCSIDKIAYIQKCWEILEGFLKDQ--PYLCGSDLTIADFCA-VATVTSVND 173
            .|||       |.     |.:..:::....::..|..|  |:|.|...::||... .|....:.|
Human    99 ALYYLVVQGKKGE-----DVLGSVRRALTHIDHSLSRQNCPFLAGETESLADIVLWGALYPLLQD 158

  Fly   174 TAPIDEFKFPKMHAW-----------------LKR---LAELPYYQE------------VNGDGA 206
            .|.:.| :...:|:|                 ||:   ||..||.|:            .|....
Human   159 PAYLPE-ELSALHSWFQTLSTQEPCQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTNEPEE 222

  Fly   207 DELKSIFKAKLA 218
            :||.::.:.::|
Human   223 EELATLSEEEIA 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_611964.1	GST_N_Delta_Epsilon	4..77	CDD:239343	7/22 (32%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	29/159 (18%)
MARS1	NP_004981.2	GST_N_5	1..74	CDD:436537	7/25 (28%)
		GST_C_MetRS_N	77..179	CDD:198340	22/121 (18%)
		PLN02610	251..893	CDD:215329
		'HIGH' region	273..283
		'KMSKS' region	593..597