DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE12 and GstE8

DIOPT Version :9

Sequence 1:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_001286571.1	Gene:	GstE8 / 37113	FlyBaseID:	FBgn0063492	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	215	Identity:	97/215 - (45%)
Similarity:	132/215 - (61%)	Gaps:	2/215 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKPALYYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTLIDGEATI 65
            |||..||....|||.||..||..|:|:..|...||.|..|.|:||||:.|||||:|||.|....|
  Fly     1 MSKLILYGTEASPPVRAAKLTLAALGIPYEYVKINTLAKETLSPEFLRKNPQHTVPTLEDDGHFI 65

  Fly    66 IDSHAICAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFAR-LRFLYEPILYYGSTDCSI 129
            .|||||.||||.||||.: .||||:|:|||.||.|||.:||.:|.. ||.:.:|:...|.|....
  Fly    66 WDSHAISAYLVSKYGQSD-TLYPKDLLQRAVVDQRLHFESGVVFVNGLRGITKPLFATGQTTIPK 129

  Fly   130 DKIAYIQKCWEILEGFLKDQPYLCGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMHAWLKRLAE 194
            ::...:.:.::.:|.||....::.|..||||||..:.::|::.....||..|:..:.||:||:.|
  Fly   130 ERYDAVIEIYDFVETFLTGHDFIAGDQLTIADFSLITSITALAVFVVIDTVKYANITAWIKRIEE 194

  Fly   195 LPYYQEVNGDGADELKSIFK 214
            ||||:|..|.||.:|.::.|
  Fly   195 LPYYEEACGKGARDLVTLLK 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	39/72 (54%)
		GstA	6..201	CDD:223698	88/195 (45%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	43/118 (36%)
GstE8	NP_001286571.1	GstA	4..196	CDD:223698	84/192 (44%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	39/72 (54%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	43/117 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468009
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118089at33392
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800