DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE12 and Clic6

DIOPT Version :9

Sequence 1:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_788267.2	Gene:	Clic6 / 304081	RGDID:	727938	Length:	613	Species:	Rattus norvegicus

Alignment Length:	193	Identity:	39/193 - (20%)
Similarity:	69/193 - (35%)	Gaps:	67/193 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KPALYYATLSPPSRAVLLTAKAIGLDLELR-PIN----LLKGEHLTPEFLKLNPQHTIPTLIDGE 62
            ||| ....|:|.:....:|     .|.|:: .:|    .|:.:.:.|.:.||..||.     :..
  Rat   423 KPA-DLQNLAPGTNPPFMT-----FDGEVKTDVNKIEEFLEEKLVPPRYPKLGTQHP-----ESN 476

  Fly    63 ATIIDSHAICAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFARLRFLYEP----ILYYG 123
            :...|..|..:..::...:....:|.|.|::     |...|||        :|..|    |..|.
  Rat   477 SAGNDVFAKFSAFIKNTKKDANDIYEKNLLR-----ALKKLDS--------YLNSPLPDEIDAYS 528

  Fly   124 STDCSIDKIAYIQKCWEILEGFLKDQPYLCGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMH 186
            :.|.::.:                 :.:|.|.:||:|| |.:                .||:|
  Rat   529 TEDVTVSQ-----------------RKFLDGDELTLAD-CNL----------------LPKLH 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	16/77 (21%)
		GstA	6..201	CDD:223698	36/190 (19%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	19/99 (19%)
Clic6	NP_788267.2	2A1904	<51..318	CDD:273344
Clic6	NP_788267.2	O-ClC	380..613	CDD:129941	39/193 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348032
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930