Protein Alignment GstE12 and Clic4

DIOPT Version :10

• Sequence 1: NP_611964.1
• Gene: GstE12 / 37960
• FlyBaseID: FBgn0027590
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_038913.1
• Gene: Clic4 / 29876
• MGIID: 1352754
• Length: 253
• Species: Mus musculus
• Alignment Length: 194
• Identity: 38/194 - (19%)
• Similarity: 63/194 - (32%)
• Gaps: 88/194 - (45%)

  Fly    27 LDLELRPI---NLLKGEH-------------------------LTPEFLKLNPQHTIPTLIDGEA 63
            :||:.:|.   ||..|.|                         ..|::|||:|:|.     :...
Mouse    57 VDLKRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHP-----ESNT 116

  Fly    64 TIIDSHA-ICAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFARLRFLYEPILYYGSTDC 127
            ..:|..| ..||:      |..:....|.::|..:.....||        .:|..|:     .|
Mouse   117 AGMDIFAKFSAYI------KNSRPEANEALERGLLKTLQKLD--------EYLNSPL-----PD- 161

  Fly   128 SIDKIAYIQKCWEILEGFLKD-----QPYLCGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMH 186
                        ||.|..::|     :.:|.|.::|:|| |.:                .||:|
Mouse   162 ------------EIDENSMEDIKFSTRRFLDGDEMTLAD-CNL----------------LPKLH 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_611964.1	GST_N_Delta_Epsilon	4..77	CDD:239343	17/78 (22%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	19/100 (19%)
Clic4	NP_038913.1	Required for insertion into the membrane. /evidence=ECO:0000250	2..101		7/43 (16%)
		O-ClC	17..252	CDD:129941	38/194 (20%)
		G-site. /evidence=ECO:0000250|UniProtKB:Q9Z0W7	35..38