Protein Alignment GstE12 and GSTA3

DIOPT Version :10

• Sequence 1: NP_611964.1
• Gene: GstE12 / 37960
• FlyBaseID: FBgn0027590
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_000838.3
• Gene: GSTA3 / 2940
• HGNCID: 4628
• Length: 222
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 59/240 - (24%)
• Similarity: 92/240 - (38%)
• Gaps: 50/240 - (20%)

  Fly     3 KPALYYAT---LSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQ-----HTIPTL- 58
            ||.|:|..   ...|.|.:|..|   |::.|.:.|.  ..|.|.    ||...     ..:|.:
Human     4 KPKLHYFNGRGRMEPIRWLLAAA---GVEFEEKFIG--SAEDLG----KLRNDGSLMFQQVPMVE 59

  Fly    59 IDGEATIIDSHAICAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFARLRFLYEPILYYG 123
            ||| ..::.:.||..|:..||     .||.|::.:||.:|.   ...|........|..|:....
Human    60 IDG-MKLVQTRAILNYIASKY-----NLYGKDIKERALIDM---YTEGMADLNEMILLLPLCRPE 115

  Fly   124 STDCSI------DKIAYIQKCWEILEGFLKDQPYLCGSDLTIADFCAVATVTSVN--DTAPIDEF 180
            ..|..|      .|..|.....::|:.  ..|.||.|:.|:.||...|..:..|.  |::.|.
Human   116 EKDAKIALIKEKTKSRYFPAFEKVLQS--HGQDYLVGNKLSRADISLVELLYYVEELDSSLIS-- 176

  Fly   181 KFPKMHAWLKRLAELPYYQEVNGDGA-----------DELKSIFK 214
            .||.:.|...|::.||..::....|:           :|.:.||:
Human   177 NFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFR 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_611964.1	GST_N_Delta_Epsilon	4..77	CDD:239343	21/81 (26%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	30/136 (22%)
GSTA3	NP_000838.3	GST_N_Alpha	4..82	CDD:239375	24/92 (26%)
		GST_C_Alpha	86..220	CDD:198317	30/140 (21%)