Protein Alignment GstE12 and GSTA2

DIOPT Version :10

• Sequence 1: NP_611964.1
• Gene: GstE12 / 37960
• FlyBaseID: FBgn0027590
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_000837.3
• Gene: GSTA2 / 2939
• HGNCID: 4627
• Length: 222
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 57/236 - (24%)
• Similarity: 98/236 - (41%)
• Gaps: 39/236 - (16%)

  Fly     3 KPALYYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQ-----HTIPTL-IDG 61
            ||.|:|:.:.....::.....|.|::.|.:.|.  ..|.|.    ||...     ..:|.: |||
Human     4 KPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIK--SAEDLD----KLRNDGYLMFQQVPMVEIDG 62

  Fly    62 EATIIDSHAICAYLVEKYGQKEQQLYPKELVQRANVDARLH--LDSGHLFARLRFLYEPILYYGS 124
             ..::.:.||..|:..||     .||.|::.::|.:|..:.  .|.|.:..        :|.:..
Human    63 -MKLVQTRAILNYIASKY-----NLYGKDIKEKALIDMYIEGIADLGEMIL--------LLPFSQ 113

  Fly   125 TDCSIDKIAYIQ-----KCWEILEGFLKD--QPYLCGSDLTIADFCAVATVTSVN--DTAPIDEF 180
            .:....|:|.||     :.:...|..||.  |.||.|:.|:.||...|..:..|.  |::.|.
Human   114 PEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLIS-- 176

  Fly   181 KFPKMHAWLKRLAELPYYQEVNGDGADELKSIFKAKLAENR 221
            .||.:.|...|::.||..::....|:.....:.:..|.|:|
Human   177 SFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESR 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_611964.1	GST_N_Delta_Epsilon	4..77	CDD:239343	18/78 (23%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	30/128 (23%)
GSTA2	NP_000837.3	GST_N_Alpha	4..82	CDD:239375	21/89 (24%)
		GST_C_Alpha	86..220	CDD:198317	33/142 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	199..222		4/19 (21%)