DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE12 and gst2

DIOPT Version :9

Sequence 1:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_588517.1	Gene:	gst2 / 2539601	PomBaseID:	SPCC965.07c	Length:	230	Species:	Schizosaccharomyces pombe

Alignment Length:	240	Identity:	59/240 - (24%)
Similarity:	90/240 - (37%)	Gaps:	70/240 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKPALYYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTLID---GE 62
            |:...||.....|....|:|..|.:.|..|....:..|||....|.|.|||...:|||:|   .:
pombe     1 MAHFTLYSHAGGPNPWKVVLALKELNLSYEQIFYDFQKGEQKCKEHLALNPNGRVPTLVDHKNND 65

  Fly    63 ATIIDSHAICAYLVEKYGQKEQQLYPKELVQRANVDARLHL--DSGHLFARLRFLY--------- 116
            .||.:|.||..||.:||                :.|.::.|  |....:..:::|:
pombe    66 YTIWESDAILIYLADKY----------------DTDRKISLSFDDPEYYKLIQYLFFQASGQGVI 114

  Fly   117 ------------EPIL-----YYGSTDCSIDKIAYIQKCWEILEGFLKDQPYLCGSDLTIADFCA 164
                        ||::     |...          |::...:||..|||:.||..:..||||...
pombe   115 WGQAGWFNFFHHEPVVSAVTRYRNE----------IKRVLGVLEDILKDRDYLVANKYTIADLSF 169

  Fly   165 V------------ATVTSVNDTAPID-EFKFPKMHAWLKRLAELP 196
            :            ...:...:...:| |.:|||.:||.:||...|
pombe   170 IPWNYNLGGLFGEGKFSFKEEVPQLDFEKEFPKAYAWNQRLLARP 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	27/75 (36%)
		GstA	6..201	CDD:223698	58/235 (25%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	29/146 (20%)
gst2	NP_588517.1	GST_N_Ure2p_like	4..84	CDD:239346	29/95 (31%)
		GstA	5..226	CDD:223698	58/236 (25%)
		GST_C_Ure2p	96..219	CDD:198326	26/129 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	54	1.000	Domainoid score	I3221
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1854
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm9258
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	0	0.000	Not matched by this tool.
	9	8.760