DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE12 and gst1

DIOPT Version :9

Sequence 1:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_588298.1	Gene:	gst1 / 2538694	PomBaseID:	SPCC191.09c	Length:	229	Species:	Schizosaccharomyces pombe

Alignment Length:	236	Identity:	59/236 - (25%)
Similarity:	91/236 - (38%)	Gaps:	62/236 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKPALYYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTLID---GE 62
            |::..|:.....|....|:...|.:.|..|.|.:|..|.|..:||.|.|||...:|||||   .:
pombe     1 MAQFTLWSHAHGPNPWKVVQALKELDLTYETRYVNFSKNEQKSPEHLALNPNGRVPTLIDHHNND 65

  Fly    63 ATIIDSHAICAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFARLRFLYEPILYYGSTDC 127
            .||.:|.||..||.:||..:.:...|::           |.:           |..::.|.....
pombe    66 YTIWESDAILIYLADKYDTERKISLPRD-----------HPE-----------YYKVIQYLFFQA 108

  Fly   128 SIDKIAYIQKCW------------------------EILEGFLKDQPYLCGSDLTIADFCAVATV 168
            |...|.:.|..|                        .:||..|||:.||..:..||||...::..
pombe   109 SGQGIIWGQAGWFSVYHQELVISAITRYRNEIKRVLGVLEDILKDRDYLVANRFTIADLSFISWN 173

  Fly   169 T-----------SVNDTAPIDEF--KFPKMHAWLKRLAELP 196
            .           |:.:..|..:|  :||:.::|.:||...|
pombe   174 NFLEIIFAEGKFSIEEEVPQLDFEKEFPRTYSWHQRLLARP 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	28/75 (37%)
		GstA	6..201	CDD:223698	58/231 (25%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	27/142 (19%)
gst1	NP_588298.1	GST_N_Ure2p_like	3..84	CDD:239346	30/80 (38%)
		GstA	5..218	CDD:223698	58/232 (25%)
		GST_C_Ure2p	96..219	CDD:198326	26/130 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	54	1.000	Domainoid score	I3221
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1854
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm9258
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	0	0.000	Not matched by this tool.
	9	8.760