DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE12 and Vars1

DIOPT Version :9

Sequence 1:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_445744.1	Gene:	Vars1 / 25009	RGDID:	3950	Length:	1264	Species:	Rattus norvegicus

Alignment Length:	192	Identity:	43/192 - (22%)
Similarity:	66/192 - (34%)	Gaps:	66/192 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 LKGEHLTPEFLKLNPQHTIPTLID---------GEATIIDSHAICAYLVEKYGQKEQQLYPKELV 92
            |||:.:...||    ..::|.:.|         |...|..:|             :|..|  |:.
  Rat   559 LKGKSVVHPFL----SRSLPIVFDDFVDMEFGTGAVKITPAH-------------DQNDY--EVG 604

  Fly    93 QRANVDARLHLDS-GHLF----------------ARLRFLYEPILYYGSTD-------CSIDKIA 133
            ||..::|...:|| |.|.                |.|..|.|..|:.|..|       |:..|
  Rat   605 QRHRLEAISIMDSKGALVNVPPPFLGLPRFEARKAVLAALKEQGLFRGIKDNPMVVPLCNRSK-- 667

  Fly   134 YIQKCWEILEGFLKDQPYL-CGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMHAWLKRLAE 194
                  :::|..|:.|.|: ||.....|.    |.||. .|...:.|......|:|:..:.:
  Rat   668 ------DVVEPLLRPQWYVRCGEMAQAAS----AAVTR-GDLRILPEAHQRTWHSWMDNIRD 718

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	10/48 (21%)
		GstA	6..201	CDD:223698	43/192 (22%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	30/128 (23%)
Vars1	NP_445744.1	GstA	<56..203	CDD:223698
		GST_C_family	92..213	CDD:295467
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..296
		PTZ00419	282..1264	CDD:240411	43/192 (22%)
		ValRS_core	335..938	CDD:185677	43/192 (22%)
		'HIGH' region	344..354
		tRNA-synt_1_2	513..640	CDD:290334	20/99 (20%)
		'KMSKS' region	862..866
		Anticodon_Ia_Val	938..1075	CDD:153416
		Val_tRNA-synt_C	1196..1258	CDD:287436
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810