DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE12 and Mars1

DIOPT Version :9

Sequence 1:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_001165053.1	Gene:	Mars1 / 216443	MGIID:	1345633	Length:	910	Species:	Mus musculus

Alignment Length:	201	Identity:	46/201 - (22%)
Similarity:	73/201 - (36%)	Gaps:	39/201 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LYYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTL-IDGEATIIDSH 69
            |:.:..||.|..||..|.......||. |:.:..|.....|| ..|:  :|.| :|....:..:.
Mouse     3 LFVSEGSPGSLPVLAAAARARGRAELL-ISTVGPEECVVPFL-TRPK--VPVLQLDSGNYLFSAS 63

  Fly    70 AICAYLVEKYGQKEQQLYPKELVQRAN-----VDARLHL------DSGHLFARLRFLYEPILYYG 123
            |||.|.....|.::..|..:.|...|.     :.|.||.      ....:...||.:...|
Mouse    64 AICRYFFLLCGWEQDDLTNQWLEWEATELQPVLSAALHCLVVQGKKGEDILGPLRRVLTHI---- 124

  Fly   124 STDCSIDKIAYIQKCWEILEGFLKDQPYLCGSDLTIADFCA-VATVTSVNDTAPIDEFKFPKMHA 187
              |.|:.:    |.|           |:|.|...::||... .|....:.|.|.:.| :...:.:
Mouse   125 --DHSLSR----QNC-----------PFLAGDTESLADIVLWGALYPLLQDPAYLPE-ELGALQS 171

  Fly   188 WLKRLA 193
            |.:.|:
Mouse   172 WFQTLS 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	21/71 (30%)
		GstA	6..201	CDD:223698	46/201 (23%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	22/114 (19%)
Mars1	NP_001165053.1	Thioredoxin_like	1..68	CDD:294274	20/68 (29%)
		GstA	<47..189	CDD:223698	32/155 (21%)
		GST_C_MetRS_N	77..179	CDD:198340	24/123 (20%)
		PRK12268	266..821	CDD:237029
		MetRS_core	267..635	CDD:173907
		'HIGH' region	275..285
		'KMSKS' region	595..599
		Anticodon_Ia_Met	644..773	CDD:153411
		MetRS_RNA	855..899	CDD:238475
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900