DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3894 and neurl1aa

DIOPT Version :9

Sequence 1:	NP_611963.5	Gene:	CG3894 / 37959	FlyBaseID:	FBgn0035059	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	XP_021330967.1	Gene:	neurl1aa / 561943	ZFINID:	ZDB-GENE-090311-3	Length:	572	Species:	Danio rerio

Alignment Length:	221	Identity:	57/221 - (25%)
Similarity:	88/221 - (39%)	Gaps:	68/221 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 FHP-YHGSNIQLGDDATVAYRRASFADALTFSERPLAPGDIFLVEIEKIERGWSGHMRLGLTELA 128
            ||| ..||.|.:........|:|||.:|:|||.||:|..:...::|.|.:..|||.:|||.|...
Zfish    62 FHPNAKGSQIVMDLAQRSVKRQASFCNAITFSNRPIALYEQVRLKITKKQCCWSGALRLGFTSKD 126

  Fly   129 PNVIRTSSEGLPHFALPDLANLGNSWIYPISKFEMNQRQDANDIIEPETDDAPHRNLLGDATHVR 193
            |:  |.:.:.||.:|.|||.:....|...:                || :.|...||:.
Zfish   127 PS--RINPDSLPKYACPDLVSQSGFWAKAL----------------PE-EFANEGNLIS------ 166

  Fly   194 TPRGLLPKRLLRPAMGNGNDSDILLTDKGSRIGIIYVPTVQSDSKGELHFIINGVDRGPVSRDIP 258
                                              .:|     |.||.:.:.||  |..|:.....
Zfish   167 ----------------------------------FWV-----DKKGRVFYRIN--DSSPMLFFSG 190

  Fly   259 LNRA-PLFVVIDVYGTTKQIRIIQLE 283
            :... ||:.:|||||.|:.:::::.|
Zfish   191 VRTTEPLWALIDVYGLTRGVQLLESE 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3894	NP_611963.5	SPRY_NHR_like	64..280	CDD:293945	56/216 (26%)
CG3894	NP_611963.5	SOCS_SOCS_like	283..321	CDD:239687	1/1 (100%)
neurl1aa	XP_021330967.1	NEUZ	59..180	CDD:128856	44/181 (24%)
		Neuralized	296..446	CDD:311244
		mRING-HC-C3HC5_NEU1A	517..560	CDD:319699
		modified RING-HC finger (C3HC5-type)	519..558	CDD:319699
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810