DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3894 and Neurl3

DIOPT Version :9

Sequence 1:	NP_611963.5	Gene:	CG3894 / 37959	FlyBaseID:	FBgn0035059	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001014122.1	Gene:	Neurl3 / 316326	RGDID:	1359633	Length:	254	Species:	Rattus norvegicus

Alignment Length:	255	Identity:	62/255 - (24%)
Similarity:	95/255 - (37%)	Gaps:	81/255 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 RQLSRFH-PYHGSNIQLGDDATVAYRRASFADALTFSERPLAPGDIFLVEIEKIERGWSGHMRLG 123
            |:...|| ...|:.:.|.|..:.|.||::|.|.:.||:||:.||:...:.:.:.|.||.|.:|:|
  Rat    15 REALSFHGDATGAQVHLDDQRSTARRRSTFHDGIVFSQRPVWPGERVALRVLRHEDGWCGGLRVG 79

  Fly   124 LTELAPNVIRTSSEGLPHFALPDLANLGNSWIYPISKFEMNQRQDANDIIEPETDDAPHRNLLGD 188
            .|.|.|..:..|.  ||.|..|||.....:|
  Rat    80 FTRLDPAQVAASC--LPPFVCPDLEEQSPTW---------------------------------- 108

  Fly   189 ATHVRTPRGLLPKRLLRPAMGNGNDSDILLTDKGSRIGIIYVPTVQSDSKGELHFIINGVDRGPV 253
                   ..|||:..:|.    ||                 |.....:.:|.|...:|......:
  Rat   109 -------AALLPEGFVRA----GN-----------------VVCFWVNRRGWLFAKVNAGRPLLL 145

  Fly   254 SRDIPLNRAPLFVVIDVYGTTKQIRIIQLEGILSLQSACRNVILESFAEDAISELPLPES 313
            .:|:.:..|||:.|:|||||||.|.::..:....:.|.                .|:|||
  Rat   146 RKDVLVQGAPLWAVMDVYGTTKAIELLDPKANAWITSG----------------EPMPES 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3894	NP_611963.5	SPRY_NHR_like	64..280	CDD:293945	56/216 (26%)
CG3894	NP_611963.5	SOCS_SOCS_like	283..321	CDD:239687	5/31 (16%)
Neurl3	NP_001014122.1	Neuralized	20..173	CDD:399869	56/216 (26%)
Neurl3	NP_001014122.1	RING-HC_NEURL3	195..236	CDD:319466
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810