DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3894 and Neurl1

DIOPT Version :9

Sequence 1:	NP_611963.5	Gene:	CG3894 / 37959	FlyBaseID:	FBgn0035059	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	XP_006231572.1	Gene:	Neurl1 / 309459	RGDID:	1307021	Length:	574	Species:	Rattus norvegicus

Alignment Length:	288	Identity:	68/288 - (23%)
Similarity:	103/288 - (35%)	Gaps:	101/288 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PSRAAYAAAEQEDPDPDQEQDR-GRESPIGS-------LECAPTLSSRKRQLS--RFHPY-HGSN 72
            ||||:..       .|...:|. |...|:.|       ..|.|.||......:  .|||: .||.
  Rat    16 PSRASRG-------HPQNLKDSIGSSFPVPSHRCHHKQKHCPPALSGGGLPATPLLFHPHTKGSQ 73

  Fly    73 IQLGDDATVAYRRASFADALTFSERPLAPGDIFLVEIEKIERGWSGHMRLGLTELAPNVIRTSSE 137
            |.:........|:|||.:|:|||.||:...:...::|.|.:..|||.:|||.|...|:  |...:
  Rat    74 ILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPS--RIHPD 136

  Fly   138 GLPHFALPDLANLGNSWIYPISKFEMNQRQDANDIIEPETDDAPHRNLLGDATHVRTPRGLLPKR 202
            .||.:|.|||.:....|                                         ...||:.
  Rat   137 SLPKYACPDLVSQSGFW-----------------------------------------AKALPEE 160

  Fly   203 LLRPAMGNGNDSDILLTDKGSRIGIIYVPTVQSDSKGELHFIIN---------GVDRGPVSRDIP 258
            .       .|:.:|:         ..:|     |.||.:.:.||         ||....
  Rat   161 F-------ANEGNII---------AFWV-----DKKGRVFYRINESAAMLFFSGVRTAD------ 198

  Fly   259 LNRAPLFVVIDVYGTTKQIRIIQLEGIL 286
                ||:.::||||.|:.::::..|.:|
  Rat   199 ----PLWALVDVYGLTRGVQLLDSELVL 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3894	NP_611963.5	SPRY_NHR_like	64..280	CDD:293945	53/225 (24%)
CG3894	NP_611963.5	SOCS_SOCS_like	283..321	CDD:239687	2/4 (50%)
Neurl1	XP_006231572.1	NEUZ	61..183	CDD:128856	42/185 (23%)
		SPRY	65..213	CDD:295394	53/221 (24%)
		Neuralized	65..130	CDD:284568	25/64 (39%)
		NEUZ	292..414	CDD:128856
		SPRY	295..446	CDD:295394
		Neuralized	296..362	CDD:284568
		zf-C3HC4_3	518..567	CDD:290631
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810