Protein Alignment Usp15-31 and UBP10

DIOPT Version :10

• Sequence 1: NP_611959.2
• Gene: Usp15-31 / 37954
• FlyBaseID: FBgn0050421
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: NP_014213.2
• Gene: UBP10 / 855535
• SGDID: S000005130
• Length: 792
• Species: Saccharomyces cerevisiae
• Alignment Length: 1055
• Identity: 168/1055 - (15%)
• Similarity: 293/1055 - (27%)
• Gaps: 474/1055 - (44%)

  Fly    24 ATATTGAIVAAGVTTTLPATKTTTTAADTSTTNAAKKIRRTFSMPRNPFRWTRKFKTAVAVTSSA 88
            |...|||..:|.::|.|.....::::.|.......::....|...|:   :....|.::....:|
Yeast   105 AADATGAKKSAELSTELSTEPPSSSSEDDKVGKEEEEEGEIFHEARD---YVEPRKASLKERDNA 166

  Fly    89 GAENDNESGKNNGARERRGSHTAISSCVGGGRGRSGSIVSLSSYEAPFISSTNNN--------TT 145
            ...:..:.|::.|  |..|..  |...:|...|.     :|.|..|....|:|.|        :|
Yeast   167 DKGDGEDIGEDIG--EDIGED--IGEDIGEDIGE-----NLGSPLATIDDSSNENEKEKRKELST 222

  Fly   146 TASNGN-------------------------NNNSSSSNINSKRTRALRRSSFRKFLNRIAQHLS 185
            :.|:.:                         ..|.|||.|:....::|.:....          :
Yeast   223 SISSDDEIEDDEDEDDMDYDSSAMEKELPEEEENDSSSKISEGEKKSLYQDLME----------N 277

  Fly   186 STVNVVSEEKHSPANRIAFIEIVPFYTGCWRRKEANKHGQPSVSGSSSGGGGGAGGPGGGER--- 247
            |||.|   .::.|.|               ..||                 .|...|.|.|.
Yeast   278 STVEV---NRYEPVN---------------NTKE-----------------NGNRNPKGEEEEEE 307

  Fly   248 -----------VPPI------GGYQ-------------------WPADQTPGV--MGLKNHGNTC 274
                       .||:      ..||                   | .|:...:  .||.|||.||
Yeast   308 EEELKHKSRSITPPVTISNLSNFYQFNENINDRGSLNSTRIVKNW-GDKFTNLKPRGLLNHGVTC 371

  Fly   275 FMNAVLQCLSHTDILAEY---FVLDQYKADLKRRNKINSRKFGTKGELTEQLANVLKALW----- 331
            :.||.:|.:.|...:..|   .::.:|.:.:            :|..::..||...|.:|
Yeast   372 YTNAAVQAMLHIPSIQHYLFDILMGKYDSTI------------SKNSVSYTLAETSKKMWLPVSK 424

  Fly   332 -TCKNESDHSTSFKAVVDR---YGTQFRSSTQHDAQEFLFWLLDKVHEDLNTASKRRYKSLKNSY 392
             ..||.|....:.|.::.|   .........|.|:.|:...|:.::.||              |.
Yeast   425 NPRKNVSASYINPKHLISRLDDINCMMSEWQQEDSHEYFMSLMSRLQED--------------SV 475

  Fly   393 GRSDEVIAAETLANHIRCNNSFVQAVFQAQFRSSLTCPRCEKQSNTFDPFHCISVQLPQLTQQTI 457
            .:..::|            .|.:..:|....:..:||..|...|.|..||:.:|:.|
Yeast   476 PKGHKLI------------ESIIYDIFGGLLKQIVTCKSCGSISKTEQPFYDLSLHL-------- 520

  Fly   458 FVTVVYMTRLPRQVRMGLRVPAGSPIVALREQLQADTGIEGSRMVLVDLNAEGFTRVFYDTQPVE 522
                                                   :|.:.:                .|..
Yeast   521 ---------------------------------------KGKKKL----------------DPNS 530

  Fly   523 TLSSIETIYCIEVPAATPVAKAATPSETGDKSAPTAVTPSPAAAQSQADLLLLVANVYRAKDGAD 587
            .||| ::|.......:|..:.|||.......|:......||.||.|                  |
Yeast   531 DLSS-DSINGTSATTSTTTSNAATKPSLSSSSSVNLNNGSPFAAAS------------------D 576

  Fly   588 ITRFGAPFSMKAPRDCSYQDLQKRMLREMAPLLKPEVFSYATPLAEMFRIRLQDPSADPDTYLEQ 652
            ::.....||::
Yeast   577 LSSANRRFSIE------------------------------------------------------ 587

  Fly   653 VEHPLLTEMIDMALSVLSSEAGPQHIKLLLEWSSPEAHFISKQQDTEEAVVEHESVARLSASKPS 717
                                      |.:.::.:||...:.|:|
Yeast   588 --------------------------KSIKDFFNPELIKVDKEQ--------------------- 605

  Fly   718 DTAALTLEQCLEHYTKAETLSAEDAWRCPHCQQYLPVVKTLGLWSLPDILVVHFKRFRQHQSKGP 782
                                   ..:.|..|.:....||...:...|:.|:||.|:||   ..|.
Yeast   606 -----------------------KGYVCEKCHKTTNAVKHSSILRAPETLLVHLKKFR---FNGT 644

  Fly   783 QAAKLTTMVKFPLTAFDMSPHLARGVHESASSSLGMGTGIGLGLGLGSNPWKKARSVDSRSSTLN 847
            .::|:...|.:|: ..|::.:
Yeast   645 SSSKMKQAVSYPM-FLDLTEY-------------------------------------------- 664

  Fly   848 SRCDAKD--TRYDLYAVCYHQGDTLETGHYTAACKNPYDRQWYKFDDQRVSKVPEDDIEQDIINN 910
              |::|:  .:|.|.:|..|:|.:|.:|||.|.||.| |..|..:||:.::.:.|.|:.::   .
Yeast   665 --CESKELPVKYQLLSVVVHEGRSLSSGHYIAHCKQP-DGSWATYDDEYINIISERDVLKE---P 723

  Fly   911 EAYMLFYQRRSVDAGECSGSSSNSGDHWVSRIAPAS-----SSSASST---SGKEREPVKLEENT 967
            .||.|.|                      :|:.|.|     :.||.:|   :.|.::...:.|..
Yeast   724 NAYYLLY----------------------TRLTPKSVPLPLAKSAMATGNVTSKSKQEQAVNEPN 766

  Fly   968 ESPAAVEVTEKAQSK 982
            ..|..:...:..:.|
Yeast   767 NRPLKINSKKNNRKK 781

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp15-31	NP_611959.2	UBP12	<255..921	CDD:227847	110/700 (16%)
UBP10	NP_014213.2	PRK05901	28..>221	CDD:235640	25/127 (20%)
		UCH	362..730	CDD:425685	106/665 (16%)