Protein Alignment Usp15-31 and DOA4

DIOPT Version :9

• Sequence 1: NP_611959.2
• Gene: Usp15-31 / 37954
• FlyBaseID: FBgn0050421
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: NP_010354.3
• Gene: DOA4 / 851641
• SGDID: S000002476
• Length: 926
• Species: Saccharomyces cerevisiae
• Alignment Length: 829
• Identity: 153/829 - (18%)
• Similarity: 234/829 - (28%)
• Gaps: 388/829 - (46%)

  Fly   124 GSIVSLSSYEAPFI---SSTNNNTTTASNGNNNN-SSSSNINSKRTRALRRSSFRKFLNRIAQHL 184
            |:.:.::..|.|.:   |.|:..|......|:|: :..:.||:|...:..|::..| |.|..|.:
Yeast   449 GNSLPINYPETPHLWKNSETDFMTNQREQLNHNSFAHIAPINTKAITSPSRTATPK-LQRFPQTI 512

  Fly   185 SSTVNVVSEEKHSPANRIAFIEIVPFYTGCWRRKEANKHGQPSVSGSSSGGGGGAGGPGGGERVP 249
            |..:|:.|....|..:.|                      |||....|:...      .....|.
Yeast   513 SMNLNMNSNGHSSATSTI----------------------QPSCLSLSNNDS------LDHTDVT 549

  Fly   250 PIGGYQWPADQTPGVMGLKNHGNTCFMNAVLQCLSHTDILAEYFVLDQYKADLKRRNKINSRKFG 314
            |...:.:..|   ..:||:|.||:|:||.::||:..|..|.:.|:.|.|...:    .||| |.|
Yeast   550 PTSSHNYDLD---FAVGLENLGNSCYMNCIIQCILGTHELTQIFLDDSYAKHI----NINS-KLG 606

  Fly   315 TKGELTEQLANVLKALWTCKNESDHS-------TSFKAVVDRYGTQFRSSTQHDAQEFLFWLLDK 372
            :||.|.:..|.::..::  |.:.|.|       ..||.......:.|::::|.|.|||..:|||.
Yeast   607 SKGILAKYFARLVHMMY--KEQVDGSKKISISPIKFKLACGSVNSLFKTASQQDCQEFCQFLLDG 669

  Fly   373 VHEDLN-------------TASKRRYK-SLKNSYGRSDEVIAAETLANHIRCNNSFVQAVFQAQF 423
            :|||||             .|..||.| ||:        :.::......:..:.|.:..:||.|:
Yeast   670 LHEDLNQCGSNPPLKELSQEAEARREKLSLR--------IASSIEWERFLTTDFSVIVDLFQGQY 726

  Fly   424 RSSLTCPRCEKQSNTFDPFHCISVQLPQLTQQTIFVTVVYMTRLPRQVRMGLRVPAGSPIVALRE 488
            .|.|.|..|...|.|:.||..:|:.:|
Yeast   727 ASRLKCKVCSHTSTTYQPFTVLSIPIP-------------------------------------- 753

  Fly   489 QLQADTGIEGSRMVLVDLNAEGFTRVFYDTQPVETLSSIETIYCIEVPAATPVAKAATPSETGDK 553
                                                                             
Yeast   754 ----------------------------------------------------------------- 753

  Fly   554 SAPTAVTPSPAAAQSQADLLLLVANVYRAKDGADITRFGAPFSMKAPRDCSYQDLQKRMLREMAP 618
                                                                             
Yeast   754 ----------------------------------------------------------------- 753

  Fly   619 LLKPEVFSYATPLAEMFRIRLQDPSADPDTYLEQVEHPLLTEMIDMALSVLSSEAGPQHIKLLLE 683
                                                                             
Yeast   754 ----------------------------------------------------------------- 753

  Fly   684 WSSPEAHFISKQQDTEEAVVEHESVARLSASKPSDTAALTLEQCLEHYTKAETLSAEDAWRCPHC 748
                                           |.:....:|:|.|...:||.|.|..::.|.||||
Yeast   754 -------------------------------KKNSRNNITIEDCFREFTKCENLEVDEQWLCPHC 787

  Fly   749 QQYLPVVKTLGLWSLPDILVVHFKRFRQHQSKGPQAAKLTTMVKFPLTAFDMSPHLAR------- 806
            ::..|..|.|.:..||..|:||.|||....:|.      ...|.:|. ..|::|..|.
Yeast   788 EKRQPSTKQLTITRLPRNLIVHLKRFDNLLNKN------NDFVIYPF-LLDLTPFWANDFDGVFP 845

  Fly   807 -GVHESASSSLGMGTGIGLGLGLGSNPWKKARSVDSRSSTLNSRCDAKDTRYDLYAVCYHQGDTL 870
             ||::                                 ..|..|......:|:||.|..|.| ||
Yeast   846 PGVND---------------------------------DELPIRGQIPPFKYELYGVACHFG-TL 876

  Fly   871 ETGHYTAACKNPYDRQWYKFDDQRVSKVPEDDIEQDIINNEAYMLFYQR 919
            ..|||||..|....:.|..|||.:...|..   :.|.||:.||:|||.|
Yeast   877 YGGHYTAYVKKGLKKGWLYFDDTKYKPVKN---KADAINSNAYVLFYHR 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp15-31	NP_611959.2	Peptidase_C19	<262..>383	CDD:271592	44/140 (31%)
		Peptidase_C19	266..>461	CDD:271592	63/215 (29%)
		Peptidase_C19R	<713..918	CDD:239139	60/212 (28%)
DOA4	NP_010354.3	RHOD	208..324	CDD:197731
		COG5533	495..924	CDD:227820	142/783 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21646
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100