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Protein Alignment Usp15-31 and USP32

DIOPT Version :9

Sequence 1:	NP_611959.2	Gene:	Usp15-31 / 37954	FlyBaseID:	FBgn0050421	Length:	1272	Species:	Drosophila melanogaster
Sequence 2:	XP_011523673.1	Gene:	USP32 / 84669	HGNCID:	19143	Length:	1634	Species:	Homo sapiens

Alignment Length:	917	Identity:	205/917 - (22%)
Similarity:	331/917 - (36%)	Gaps:	304/917 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 WPADQT----------------PGVMGLKNHGNTCFMNAVLQCLSHTDILAEYFVLDQYKADLKR 304
            ||.:.:                .|..||.|.|||||||:.:||:|:|..|.:||:..::..:|.|
Human   739 WPEEMSFIANSSKIDRHKVPTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNR 803

  Fly   305 RNKINSRKFGTKGELTEQLANVLKALWTCKNESDHSTSFKAVVDRYGTQFRSSTQHDAQEFLFWL 369
            .|.|     |.||.:.:...::::.||:...::......:..:.:|..:|....|.|:||.|.:|
Human   804 TNPI-----GMKGHMAKCYGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFNGFQQQDSQELLAFL 863

  Fly   370 LDKVHEDLNTASKRRYKSLKNSYGRSDEVIAAETLANHIRCNNSFVQAVFQAQFRSSLTCPRCEK 434
            ||.:|||||...::.|..||:|.||.|..:|||...||:|.|.|.|..:|..|.||.:.|..|..
Human   864 LDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSIVVDLFHGQLRSQVKCKTCGH 928

  Fly   435 QSNTFDPFHCISVQLPQLTQQTIFVTVVYMTRLPRQVRMGLRVPAGSPIVALREQLQADTGIEGS 499
            .|..||||:.:|:.||..:...:.:||:.:.. ...||.|||:........|::||....|:...
Human   929 ISVRFDPFNFLSLPLPMDSYMHLEITVIKLDG-TTPVRYGLRLNMDEKYTGLKKQLSDLCGLNSE 992

  Fly   500 RMVLVDLNAEGFTRVFYDTQPVETLSSIETIYC-IEVPAATPVAKAATPSETGDKSAPTAVTPSP 563
            :::|.:::.........|.|.|..  |:....| .|:|.......|::|::|...|:|
Human   993 QILLAEVHGSNIKNFPQDNQKVRL--SVSGFLCAFEIPVPVSPISASSPTQTDFSSSP------- 1048

  Fly   564 AAAQSQADLLLLVANVYRAKDGADITR-----FGAPFS------------------MKAPRDCSY 605
                |..::..|..|       .|:.|     .|.|.:                  |.:..|..:
Human  1049 ----STNEMFTLTTN-------GDLPRPIFIPNGMPNTVVPCGTEKNFTNGMVNGHMPSLPDSPF 1102

  Fly   606 QD----LQKRMLREMAPLL-----KPEVFSYATPLAEMFRIRLQDPSADPDTYLEQVEHPLLTEM 661
            ..    :.::|:|.....|     :|.:|.....:......|.:|                |.:.
Human  1103 TGYIIAVHRKMMRTELYFLSSQKNRPSLFGMPLIVPCTVHTRKKD----------------LYDA 1151

  Fly   662 IDMALSVLSSEAGPQHIK----------------------------------------------- 679
            :.:.:|.|:|...||...
Human  1152 VWIQVSRLASPLPPQEASNHAQDCDDSMGYQYPFTLRVVQKDGNSCAWCPWYRFCRGCKIDCGED 1216

  Fly   680 --------LLLEWSSPEAHFISKQQDTEEAVVEHESVARLSASKPSDTAALTLEQCLEHYTKAET 736
                    :.::| .|.|..:..|...|..|.|||||.:   |:.:....:.|:.||..:|..|.
Human  1217 RAFIGNAYIAVDW-DPTALHLRYQTSQERVVDEHESVEQ---SRRAQAEPINLDSCLRAFTSEEE 1277

  Fly   737 LSAEDAWRCPHCQQYLPVVKTLGLWSLPDILVVHFKRFRQHQSKGPQAAKLTTMVKFPLTAFD-- 799
            |...:.:.|..|:.:....|.|.||.||.||::|.|||:....:..::.|:   ||||..:||
Human  1278 LGENEMYYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNGRWIKSQKI---VKFPRESFDPS 1339

  Fly   800 ---------------MSPH---------LARGVHE------------------------------ 810
                           ::|.         |||.|.:
Human  1340 AFLVPRDPALCQHKPLTPQGDELSEPRILAREVKKVDAQSSAGEEDVLLSKSPSSLSANIISSPK 1404

  Fly   811 -SASSSLGMGTGI--GLGLGLGSNPWKKARS--------VDSRSSTLNSR--------------C 850
             |.|||...||..  .......|:|....||        :.|::...:|:              |
Human  1405 GSPSSSRKSGTSCPSSKNSSPNSSPRTLGRSKGRLRLPQIGSKNKLSSSKENLDASKENGAGQIC 1469

  Fly   851 D------------------------------------------------------------AKDT 855
            :                                                            .:||
Human  1470 ELADALSRGHVLGGSQPELVTPQDHEVALANGFLYEHEACGNGYSNGQLGNHSEEDSTDDQREDT 1534

  Fly   856 R----YDLYAVCYHQGDTLETGHYTAACKNPYDRQWYKFDDQRVSKVPEDDIEQDIINNEAYMLF 916
            |    |:|||:..|.| .|..|||....||| :.:||.::|....::..|:|:.|    .||:||
Human  1535 RIKPIYNLYAISCHSG-ILGGGHYVTYAKNP-NCKWYCYNDSSCKELHPDEIDTD----SAYILF 1593

  Fly   917 YQRRSVD 923
            |:::.:|
Human  1594 YEQQGID 1600

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.