Protein Alignment Usp15-31 and Usp20

DIOPT Version :10

• Sequence 1: NP_611959.2
• Gene: Usp15-31 / 37954
• FlyBaseID: FBgn0050421
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: NP_083122.1
• Gene: Usp20 / 74270
• MGIID: 1921520
• Length: 916
• Species: Mus musculus
• Alignment Length: 824
• Identity: 178/824 - (21%)
• Similarity: 281/824 - (34%)
• Gaps: 283/824 - (34%)

  Fly   167 ALRRSSFRKFLNRIAQHLSSTVNVVSEEKHSPANRIAFIEIVPFYTGCWRRKEANKHGQPSVSGS 231
            |..|..|.:  .|:|.||:|:...:||:...|.:..  ::.||.........|:...
Mouse    85 ACEREVFLE--QRLAVHLASSSARLSEQDSPPPSHP--LKAVPIAVADEGESESEDD-------- 137

  Fly   232 SSGGGGGAGGPGGGERVPPIGGYQWPADQTP-GVMGLKNHGNTCFMNAVLQCLSHTDILAEYFVL 295
                                       |..| |:.|:||.||:|:|||.||.||:...|.::|:
Mouse   138 ---------------------------DLKPRGLTGMKNLGNSCYMNAALQALSNCPPLTQFFL- 174

  Fly   296 DQYKADLKRRNKINSRKFGTKGELTEQLANVLKALWTCKNES-DHSTSFKAVVDRYGTQFRSSTQ 359
              ....|.|.:|        |..|.:....::..:|..|..| ...||....:......||...|
Mouse   175 --ECGGLVRTDK--------KPALCKSYQKLISEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQ 229

  Fly   360 HDAQEFLFWLLDKVHEDLNTASKRRYKSLKNSYGRSDEVIAAETLANHIRCNNSFVQAVFQAQFR 424
            .|.||||..|:|::||:|                 .:.::||.......|.::|
Mouse   230 QDTQEFLRCLMDQLHEEL-----------------KEPMVAAVAALTDARDSDS----------- 266

  Fly   425 SSLTCPRCEKQSNTFDPF-HCISVQ------------LPQLTQQTIFVTVVYMTRLPRQVRMGLR 476
            |.....|...:|.:.|.| .|.|..            .....:..:.::......:..:.||..|
Mouse   267 SDTDERRDGDRSPSEDEFLSCDSSSDRGEGDGQGRGGGSSKAEMELLISDEAGRAISEKERMKDR 331

  Fly   477 VPAGSPIVALREQLQADTGIEGSRMVLVDLNAEGFTRVFYDTQPVET------------------ 523
            ..:........||:..|..::.:...|.:.:.|........|.|.:|
Mouse   332 KFSWGQQRTNSEQVDEDADVDTAMASLDEQSREAQPPSPRSTSPCQTPEPDNEAHIRSSSRPCSP 396

  Fly   524 ----------LSSIETIYCIEVPAATPV--------AKAATPSETGDKSAPTAVTPSPAAAQSQA 570
                      |||       ..|.|:||        .||..||..|.:             :.:.
Mouse   397 VHHHHEGHSKLSS-------SPPRASPVRMGPSYVLKKAQVPSTGGRR-------------RKEQ 441

  Fly   571 DLLLLVANVYRAKDGADITRFGAPFSMKAPRDC--------SYQDLQKRMLREMAPLLKPEVFSY 627
            ....::::|:.          |:..|:.....|        ::|||.       .|:...|
Mouse   442 SYRSVISDVFN----------GSVLSLVQCLTCDRVSTTVETFQDLS-------LPIPGKE---- 485

  Fly   628 ATPLAEMFRIRLQDPSADP----DTYLEQVEHPLLTEMIDMALSVLSSEAGPQHIKLLLEWSSPE 688
              .||::.....|:..|.|    |:|..|                              .|.:
Mouse   486 --DLAKLHSAIYQNVPAKPGACGDSYSSQ------------------------------GWLA-- 516

  Fly   689 AHFISKQQDTEEAVVEHESVARLSAS-KPS--DTAALTLEQCLEHYTKAETLSAEDAWRCPHCQQ 750
                        .:||:  :.|...| .||  ....:|||.||..:..|:.|..::.:.|..|::
Mouse   517 ------------FIVEY--IRRFVVSCTPSWFWGPVVTLEDCLAAFFAADELKGDNMYSCERCKK 567

  Fly   751 YLPVVKTLGLWSLPDILVVHFKRFRQHQSKGPQAAKLTTMVKFPLTAFDMSPHLARGVHESASSS 815
            ....||...:..||:||.||.|||| |:..  .:.|:::.|.|||...|:.|.||:
Mouse   568 LRNGVKYCKVLCLPEILCVHLKRFR-HEVM--YSFKVSSHVSFPLEGLDLRPFLAK--------- 620

  Fly   816 LGMGTGIGLGLGLGSNPWKKARSVDSRSSTLNSRCDAKDTRYDLYAVCYHQGDTLETGHYTAACK 880
                                             .|.::.|.|||.:|..|.| |..:|||.|.|:
Mouse   621 ---------------------------------ECTSQVTTYDLLSVICHHG-TAGSGHYIAYCQ 651

  Fly   881 NPYDRQWYKFDDQRVSKVPEDDIEQDIINNEAYMLFYQRRSVDA 924
            |..:.|||:||||.|::|.|..::    |.|||:|||::.|.:|
Mouse   652 NVINGQWYEFDDQYVTEVHETVVQ----NVEAYVLFYRKSSEEA 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp15-31	NP_611959.2	UBP12	<255..921	CDD:227847	162/731 (22%)
Usp20	NP_083122.1	zf-UBP	30..90	CDD:460464	2/4 (50%)
		UBP12	<73..688	CDD:227847	176/819 (21%)
		UCH	145..684	CDD:425685	157/716 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	258..420		27/179 (15%)
		DUSP	704..787	CDD:197831
		DUSP	812..896	CDD:197831