Protein Alignment Usp15-31 and Usp19

DIOPT Version :9

• Sequence 1: NP_611959.2
• Gene: Usp15-31 / 37954
• FlyBaseID: FBgn0050421
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: XP_006511895.1
• Gene: Usp19 / 71472
• MGIID: 1918722
• Length: 1361
• Species: Mus musculus
• Alignment Length: 1186
• Identity: 278/1186 - (23%)
• Similarity: 426/1186 - (35%)
• Gaps: 368/1186 - (31%)

  Fly    12 EGDAATTHLTTTATATTGAIVAAGVTTTLPATKTTTTAADTSTTNAAKKIRRTFSMPRNPFRWTR 76
            :|| |.:.|:.:||.     |.|......|...|.|:...:..:.|...:.:|.| |||.
Mouse   228 QGD-APSFLSDSATQ-----VEAEEKLCAPPMNTQTSLLSSEKSLALLTVEKTVS-PRND----- 280

  Fly    77 KFKTAVAVTSSAGAENDNESGKNNGARERRGSHTAISSCVGGGRGRSGSIVSLSSYEAPFISSTN 141
                  .|......:.|.|..:.:..:|.                     ::|.:.....:....
Mouse   281 ------PVAPVMVQDRDPEPEQEDQVKEE---------------------MALGADPTALVEEPE 318

  Fly   142 N--NTTTASNGNNNNSSSSNINSKRTRALRRSS----FRK------FLNRIAQHL-------SST 187
            :  |.....|.:......|.:.....:.:||.|    ||:      |..|....|       ..|
Mouse   319 SMVNLAFVKNDSYEKGPDSVVVHVYVKEIRRDSSRVLFREQDFTLIFQTRDGNFLRLHPGCGPHT 383

  Fly   188 V--------NVVSEEKHSPANRIAFIEIVPFYTGCWRRKEANKHG---QPSVSGSSSGG------ 235
            :        |::..|:.:.....:.|:|      |.|::::.:.|   .|:..|:..|.
Mouse   384 IFRWQVKLRNLIEPEQCTFCFTASRIDI------CLRKRQSQRWGGLEAPATRGAVGGAKVAVPT 442

  Fly   236 ----------GGG------------------------AGGPGGGERVP----------------- 249
                      |||                        :|..|...|.|
Mouse   443 GPTPLDSTPPGGGPHPLTGQEEARAVEKEKPKARSEDSGLDGVVARTPLEHVAPKPDPHLASPKP 507

  Fly   250 ----------PIGGYQWPADQ-------TPGVMGLKNHGNTCFMNAVLQCLSHTDILAEYFVLDQ 297
                      |:.|.....|:       .||..||.|.|||||||:|:|.||:|..|.::|....
Mouse   508 TCMVPPMPHSPVSGDSVEEDEEEEKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRS 572

  Fly   298 YKADLKRRNKINSRKFGTKGELTEQLANVLKALWTCKNESDHSTSFKAVVDRYGTQFRSSTQHDA 362
            ::|::...|.:     ||.|.|....|.:|:|||...:::...:..||:|....:||....||||
Mouse   573 FEAEINYNNPL-----GTGGRLAIGFAVLLRALWKGTHQAFQPSKLKAIVASKASQFTGYAQHDA 632

  Fly   363 QEFLFWLLDKVHEDLNTASKRRYKSLKNSYGRSDEVIAAETLANHIRCNNSFVQAVFQAQFRSSL 427
            |||:.:|||.:|||||....:.|....:|.||.|||:|.|....|...|:||:..:||.|::|.|
Mouse   633 QEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKL 697

  Fly   428 TCPRCEKQSNTFDPFHCISVQLPQLTQQTIFVTVVYMTRLPRQVRMGLRVPA---GSPIVALREQ 489
            .||.|.|.|.|||||..:.|.|||  :|.: :.:.|..|.|....:...|..   .|....:.:.
Mouse   698 VCPVCAKVSITFDPFLYLPVPLPQ--KQKV-LPIFYFAREPHSKPIKFLVSVSKENSSASEVLDS 759

  Fly   490 LQADTGIEGSRMVLVDLNAEGFTRVFYDTQPVETLSSIETIYCIEVPAATPVAKAATPSETGDKS 554
            |.....::...:.|.::....|.|||..:..::.:|..:.:.|.|:.:.....:.....|...:.
Mouse   760 LSQSVHVKPENLRLAEVIKNRFHRVFLPSHSLDAVSPTDVLLCFELLSPELAKERVVVLEVQQRP 824

  Fly   555 APTAVTPSPAAA-----QSQADLLLLVANVYRA------------KDGADITR---FGAPFSMKA 599
            ...::..|..||     ||:.:.|......||.            .|...:.|   .|.||.:..
Mouse   825 QVPSIPISKCAACQRKQQSEEEKLKRCTRCYRVGYCNQFCQKTHWPDHKGLCRPENIGYPFLVSV 889

  Fly   600 PRDCSYQDLQKRMLREMAPLLKPEVFSYATPLAEMFR---------------------------- 636
            |       ..:.....:|.||:    .||.....:|:
Mouse   890 P-------ASRLTYARLAQLLE----GYARYSVSVFQPPFQPGRMALESQSPGCTTLLSTSSLEA 943

  Fly   637 ------------IRLQDPSADPDTYLEQVEHPLLTEMIDMALSVLSSE---AGP-QHIKLLL--E 683
                        ::|..|.|:.||...:|..|.....:. :.|.||||   :|| :...||.  .
Mouse   944 GDSEREPIQPSELQLVTPVAEGDTGAHRVWPPADRGPVP-STSGLSSEMLASGPIEGCPLLAGER 1007

  Fly   684 WSSPEAHFISKQQDTEEAVVEHE-------------------------------SVA-------R 710
            .|.||| .:...|.:.|:|..|.                               |:|       |
Mouse  1008 VSRPEA-AVPGYQHSSESVNTHTPQFFIYKIDASNREQRLEDKGETPLELGDDCSLALVWRNNER 1071

  Fly   711 L------------------SASKPSDTAALTLEQCLEHYTKAETLSAEDAWRCPHCQQYLPVVKT 757
            |                  ||.:.:.....||:|||..:|:.|.|:.|:||.||.|:|:....|.
Mouse  1072 LQEFVLVASKELECAEDPGSAGEAARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQ 1136

  Fly   758 LGLWSLPDILVVHFKRF-------RQHQSKGPQAAKLTTMVKFPLTAFDMSPHLARGVHESASSS 815
            |.||.||::|:|..|||       |.         |:..:|:||:...|:|...
Mouse  1137 LLLWRLPNVLIVQLKRFSFRSFIWRD---------KINDLVEFPVRNLDLSKFC----------- 1181

  Fly   816 LGMGTGIGLGLGLGSNPWKKARSVDSRSSTLNSRCDAKDTRYDLYAVCYHQGDTLETGHYTAACK 880
                  ||          :|...:.|               ||||||..|.|..: .|||||..:
Mouse  1182 ------IG----------QKEEQLPS---------------YDLYAVINHYGGMI-GGHYTACAR 1214

  Fly   881 NPYDRQ-------WYKFDDQRVSKVPEDDIEQDIINNEAYMLFYQRRSVDAGECSGSSSNSGDHW 938
            .|.||.       |..|||..|:.|.    |..::...||:|||:||:... |....:|:|..|
Mouse  1215 LPNDRSSQRSDVGWRLFDDSTVTTVD----ESQVVTRYAYVLFYRRRNSPV-ERPPRASHSEHH- 1273

  Fly   939 VSRIAPASSSSASSTS 954
             ..:.||:.::||..|
Mouse  1274 -PDLGPAAEAAASQAS 1288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp15-31	NP_611959.2	Peptidase_C19	<262..>383	CDD:271592	50/120 (42%)
		Peptidase_C19	266..>461	CDD:271592	81/194 (42%)
		Peptidase_C19R	<713..918	CDD:239139	65/218 (30%)
Usp19	XP_006511895.1	p23_like	58..140	CDD:107220
		p23_CS_SGT1_like	329..425	CDD:107223	17/101 (17%)
		USP19_linker	416..538	CDD:374662	14/121 (12%)
		UBP12	<536..1258	CDD:227847	214/798 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5560
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1283205at2759
OrthoFinder	1	1.000	-	-		FOG0000596
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820