Protein Alignment Usp15-31 and usp31

DIOPT Version :9

• Sequence 1: NP_611959.2
• Gene: Usp15-31 / 37954
• FlyBaseID: FBgn0050421
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: XP_005164285.1
• Gene: usp31 / 564487
• ZFINID: ZDB-GENE-100210-4
• Length: 1303
• Species: Danio rerio
• Alignment Length: 1211
• Identity: 371/1211 - (30%)
• Similarity: 551/1211 - (45%)
• Gaps: 222/1211 - (18%)

  Fly   155 SSSSNINSKRT----RALRRSSFR---KFLNRIAQHLSSTVNVVSEEKHSPANRIAFIEIVPFYT 212
            ||.|:...|::    :..||.|.|   .|::|:.:.| ||::....|.|:|
Zfish     2 SSKSSSKEKKSGFSKKLFRRGSVRSVGSFMSRVLKTL-STLSHFGSELHAP-------------- 51

  Fly   213 GCWRRKEANKHGQPSVSGSSSGGGGGAGGPGGGERVPPIGGYQWPADQTPGVMGLKNHGNTCFMN 277
                      .|:....|.:|....|.|.....|  ...||: ...|:.|||.||||||||||||
Zfish    52 ----------DGEKDDGGFTSFKNEGKGSVASDE--SDCGGF-LSRDKIPGVAGLKNHGNTCFMN 103

  Fly   278 AVLQCLSHTDILAEYFVLDQYKAD-----LKRRNKINSRKFG-TKGELTEQLANVLKALWTCKNE 336
            |:|||||:|::.|||..|:||:.|     ..:.|.:..||.. .:||:||||:.:::||||.:..
Zfish   104 AILQCLSNTELFAEYLALEQYRGDQTDDEKPKTNGVVGRKGAQDRGEVTEQLSGLVRALWTFEYT 168

  Fly   337 SDHSTSFKAVVDRYGTQFRSSTQHDAQEFLFWLLDKVHEDLNTASKRRYK-SLKNSYGRSDEVIA 400
            ..||..||..|.|...|:|.:.||||||||.||||:||||||.......: |:|......|..:.
Zfish   169 PQHSRDFKNAVSRSAMQYRGNAQHDAQEFLLWLLDRVHEDLNHLVHPNIRGSVKPPTEEDDAALE 233

  Fly   401 AET--LANHIRCNNSFVQAVFQAQFRSSLTCPRCEKQSNTFDPFHCISVQLPQLTQQTIFVTVVY 463
            ..:  |:     ..||||.:||||:|||||||.|:|||||||||.|||:.:|....:.::|||||
Zfish   234 GPSPPLS-----AGSFVQELFQAQYRSSLTCPHCQKQSNTFDPFLCISLPIPLPHTRPLYVTVVY 293

  Fly   464 MTRLPRQVRMGLRVPAGSPIVALREQLQADTGIEGSRMVLVDLNAEGFTRVFY-DTQPVETLSSI 527
            ..:....:|:|:.||..|.:..|||.:..:|.|...:.||.::..:||.|.|. |...::.:...
Zfish   294 QGKYSHCMRIGVAVPLNSTVSRLREAVSRETKIPPDQFVLTEMYYDGFHRSFCDDDDDLDIIQES 358

  Fly   528 ETIYCIEVPAATPVAKAATPS------------ETGDKSAPT------AVTP-SPAAAQSQADLL 573
            ::::..|.|....:....:..            :.|.:|:.|      ||.| ||........::
Zfish   359 DSVFAFETPETFRLENIRSKRGSLLANLNQNNLKYGAESSRTPSFMQGAVNPASPNKNTGSEKMI 423

  Fly   574 LLVANVYRAKDGADITRFGAPFSMKAPRDCSYQDLQKRMLREMAPLLKPEVFSYATPLAEMFRIR 638
            ||:.|  ||..|....|||.||.:...|..::..|||.:|.:|..|.:|.|:....|    |.:|
Zfish   424 LLICN--RACTGHQGRRFGLPFVLYLERSVTWDVLQKEILEKMRHLTRPGVYVQIGP----FSLR 482

  Fly   639 LQDPSADPDTY-LEQVEHPLLTEMIDMALSVLSSEAGPQHIKLLLEWSSPEAHFISKQQDTEEAV 702
            :  ......|| |.|.|.||....::.|.. .....||.|:|:::||......::....: ||.:
Zfish   483 V--VGVVGITYLLPQEEQPLCHPTVERAYK-SCGPGGPPHVKIVVEWDKETKEYLFGHTE-EEYI 543

  Fly   703 VEHESVARLSASKPSDTAALTLEQCLEHYTKAETLSAEDAWRCPHCQQYLPVVKTLGLWSLPDIL 767
            .:.||| .|...:.....|.||.||.:.|||.|.|:.:||||||||:|.......|.||:|||:|
Zfish   544 PDAESV-YLHREQHHQPQACTLAQCFQLYTKEEQLAPDDAWRCPHCRQLQQGRIKLSLWTLPDVL 607

  Fly   768 VVHFKRFRQHQSKGPQAAKLTTMVKFPLTAFDMSPHLARGVHESASSSLGMGTGIGLGLGLGSNP 832
            ::|.|||||   :|.:..|:..||:|||...||:||:.:....|.|            |....:|
Zfish   608 ILHLKRFRQ---EGDRRVKMQNMVRFPLLGMDMAPHVVKRSQSSWS------------LPSHWSP 657

  Fly   833 WKK----ARSVDSRSSTLNSRCDAKDTRYDLYAVCYHQGDTLETGHYTAACKNPYDRQWYKFDDQ 893
            |::    .|:.|             |..|||||||.|.|: :..|||||.|||..|.|||.|||.
Zfish   658 WRRPYGLGRNPD-------------DYLYDLYAVCNHHGN-MHGGHYTAYCKNSIDGQWYCFDDS 708

  Fly   894 RVSKVPEDDIEQDIINNEAYMLFYQRR------SVDAGECSGSSSNSGDHWVSRIAPAS--SSSA 950
            .|..|.::|:.|    ..||:||||||      |.::.....:||:..:|||:|: |.|  .|.|
Zfish   709 EVQPVADEDVCQ----QTAYILFYQRRTTIPSWSANSSVAGSTSSSLCEHWVNRL-PGSRPPSLA 768

  Fly   951 SSTSGKEREPVKLEENTESPA------AVEVTEKAQSKPVDIVCQDKAKGTADGP--DADQEQTT 1007
            |..|.:....:.|.|:.|.|.      |:.:|.......:        :|.:..|  .:.|.|:.
Zfish   769 SGASSRRTSLISLAESVEFPGDRSEDDALALTNTGSPALL--------RGFSTRPFVRSIQRQSL 825

  Fly  1008 VPHDLQIEELAFADADVDTSLGETIK--------AEVNLAAKDEPKKVEVEEA------------ 1052
            .........|||::..:..|...:.|        :.::|.::..|....:.||
Zfish   826 SSRSSVTSPLAFSENGMKPSWSLSTKLQMRSNSPSRLSLDSRSSPPLERIGEACDDKVSTSCFGG 890

  Fly  1053 -----------TPIFAMDEDGSE-------------------ARQEKKEECVKKEDELSEAPDVS 1087
                       .|:..|:.:||:                   .::..|.|.|...:::: |.|.:
Zfish   891 YSRHERQPSSKAPLAMMEGNGSDDGNGKRILDEAYCRAPLQADKKSSKGEPVDNNNQIN-AVDQN 954

  Fly  1088 ELTAESKTNGHVSSSSSSSSSESSLSSR---------SSPRSLSTSVTAASTLQSKFNGHMSAAP 1143
            .|...||...|.||...:..|.|..||.         |..|..::|||.:.:.|      :|::|
Zfish   955 SLGPLSKEQKHKSSEKKTEGSGSKKSSTKTKGDQEKPSKKRQSTSSVTKSPSSQ------VSSSP 1013

  Fly  1144 ALFNGNGNTS--QLSSSLQLSRHVLHNHQWHGSRSSVSAVENATQHQQQQAAASLSLRHSFSTSS 1206
            .: .|...|:  :.|:|.:.::............||.|.|...|     :...||:.....|.|.
Zfish  1014 QV-KGTKTTNLKEKSNSPKSTKGTPSGTPSRKKESSESPVSGGT-----KGKPSLTSTPQSSASP 1072

  Fly  1207 NYTETLSSLLRKSANTCSKDTLLFIDQQSHH---HTAGLIE 1244
            :.|...||.|.:..:...|..|  :::.|..   ||:.|.|
Zfish  1073 SPTSKKSSSLAERNSVSGKKKL--VERGSSKDLTHTSPLAE 1111

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp15-31	NP_611959.2	Peptidase_C19	<262..>383	CDD:271592	68/126 (54%)
		Peptidase_C19	266..>461	CDD:271592	99/203 (49%)
		Peptidase_C19R	<713..918	CDD:239139	83/208 (40%)
usp31	XP_005164285.1	UBP12	<82..732	CDD:227847	263/698 (38%)
		Peptidase_C19	92..>302	CDD:271592	103/214 (48%)
		Peptidase_C19R	<562..729	CDD:239139	82/199 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	399	1.000	Domainoid score	I704
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	440	1.000	Inparanoid score	I1636
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1283205at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25166
orthoMCL	1	0.900	-	-		OOG6_105957
Panther	1	1.100	-	-	O	PTHR21646
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2490
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.970