Protein Alignment Usp15-31 and Usp32

DIOPT Version :10

• Sequence 1: NP_611959.2
• Gene: Usp15-31 / 37954
• FlyBaseID: FBgn0050421
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: NP_001262074.2
• Gene: Usp32 / 40169
• FlyBaseID: FBgn0036913
• Length: 1779
• Species: Drosophila melanogaster
• Alignment Length: 1056
• Identity: 223/1056 - (21%)
• Similarity: 340/1056 - (32%)
• Gaps: 396/1056 - (37%)

  Fly   236 GGGAGGPGGGERVPPIGGYQWPADQTPGVMGLKNHGNTCFMNAVLQCLSHTDILAEYFVLDQYKA 300
            |.|||.||...|:.........|   ||..||.|.||||||||.||.|.:|..||:||..:.::.
  Fly   715 GQGAGTPGDRRRLTRSSIMSVHA---PGATGLHNLGNTCFMNAALQVLFNTQPLAQYFQREMHRF 776

  Fly   301 DLKRRNKINSRKFGTKGELTEQLANVLKALWTCKNESDHSTSFKAVVDRYGTQFRSSTQHDAQEF 365
            ::...||:     ||||:|..:.|.:||.:||....|......:..|::|..||....|||:||.
  Fly   777 EVNAANKL-----GTKGQLAMRYAELLKEVWTATTRSVAPLKLRFCVNKYAPQFAGGGQHDSQEL 836

  Fly   366 LFWLLDKVHEDLNTASKRRYKSLKNSYGRSDEVIAAETLANHIRCNNSFVQAVFQAQFRSSLTCP 430
            |.||||.:|||||...::.|..||:|.||.|:::|||..:.|...|.|.:..:|..|.:|.::|.
  Fly   837 LEWLLDALHEDLNRVMEKPYSELKDSNGRPDKIVAAEAWSQHHARNQSIIIDLFYGQLKSKVSCL 901

  Fly   431 RCEKQSNTFDPFHCISVQLPQLTQQTIFVTVVYMTRLPRQVRMGLRVPAGSPIVALREQLQADTG 495
            .|..:|..||||..:|:.|| :.....|..:|.:......::.|.|:.:......|:.:|.....
  Fly   902 GCGHESVRFDPFSLLSLPLP-VENYIYFEVLVILLDGSVPIKYGFRLNSDCKYSHLKHKLSTMCS 965

  Fly   496 IEGSRMVLVDLNAEGFTRVFYDTQPVETLSSIETIYCIEVPAAT--------------------- 539
            :..:.|::.:|......:|..|.:.:.|.|:.| :|..::|..:
  Fly   966 LPPNLMLVCELWNSQIRQVLNDDEKLRTQSAKE-LYVYQLPEQSMRTRSNSGLSMHIEQGLKDIQ 1029

  Fly   540 -------------------------------------------------------------PVAK 543
                                                                         |:..
  Fly  1030 RSSALITSAQDSLSSLSTLQTSSHRASSRVLCNGHVSGLDVEGEAEVGTDVSQCNSNSNYNPIVS 1094

  Fly   544 AATPSETGD-------------------------------------KSAPTAVTPSPAAAQ---- 567
            ..:.:.:||                                     .|:|.......||||
  Fly  1095 TYSGNGSGDNQVHELLPDEAGKVSRCFGKRECMPHSLFCFKESLILSSSPENTFMHGAAAQQKRV 1159

  Fly   568 SQADLLLLVANV----YRAKDG--------------ADITRFGAPFSMK---APRDCSYQ----- 606
            |.|.||...:|.    |....|              ||:    .|.|.:   ...||||:
  Fly  1160 SSAKLLHTESNTSSMSYTNHSGENSMESSLTEPIPLADL----EPVSSRNGSGGEDCSYRTSPND 1220

  Fly   607 --------------DLQKRMLR---------EMAPLLKPEV------------------------ 624
                          |:.::...         :.....:||.
  Fly  1221 SSGLSTGHTLGASLDVDEQAEEGNAEDHDQPDQITTSQPETSSGVYSRRSSQPPHKAGKYLVAVH 1285

  Fly   625 ----------FSYATPLAEMFRIRLQDPSADPDTYLE-------QVEH-----PLLTEMIDMA-- 665
                      .||......:|.:.|..|:::..|:.:       ||..     |..||..:.|
  Fly  1286 RKITRHDSYFLSYHKTRPSLFGVPLLIPNSEGGTHKDLYCAVWLQVSRLLSPLPATTEQANHAAD 1350

  Fly   666 ----------------------------------------------------------------- 665
                                                                             
  Fly  1351 CDDSLGYDFPFTLRAVKADGLTCAICPWSSFCRGCEIRCNNDYVLQGALPPINAAASNTSTPKMN 1415

  Fly   666 -----LSVLSSEAGPQH---------------IKLLLEWSSPEAHFISKQQDTEEAVVEHESVAR 710
                 |..|.::..|::               ..:.::| .|.|..:..|...|...|:||::|
  Fly  1416 AKFPSLPNLEAKRTPEYTASLSYTPTTKYFEDFTIAIDW-DPTALHLRYQSTLERLWVDHETIA- 1478

  Fly   711 LSASKPSDTAALTLEQCLEHYTKAETLSAEDAWRCPHCQQYLPVVKTLGLWSLPDILVVHFKRFR 775
              .|:......:.|..||..:|..|.|  |..:.|.||:...|..|.|.:|.||.||:||.|||.
  Fly  1479 --ISRREQVEPVDLNHCLRAFTSEEKL--EQWYHCSHCKGKKPATKKLQIWKLPPILIVHLKRFN 1539

  Fly   776 QHQSKGPQAAKLTTMVKFPLTAFDMSPHLA----------------------------------- 805
            ....|..::.|   :|.||...||.:|:||
  Fly  1540 CVNGKWVKSQK---VVHFPFDDFDPTPYLASVPQETILRHKELLELKNDAEMTMATNEVVSELDE 1601

  Fly   806 -----RGVHESASSSLGM--------GTGIGLGLGLGSNPWKKARSV---------------DSR 842
                 :.|.|...:..|.        .||..|......|..::.|.:               |..
  Fly  1602 IDAPSKEVKEELPNQTGSTKATASPPPTGNILRQSKTKNAVRRQRLISTSLTKTPIVDGEFEDYH 1666

  Fly   843 SSTLNSRCDAKDTRYDLYAVCYHQGDTLETGHYTAACKNPYDRQWYKFDDQRVSKVPEDDIEQDI 907
            ...|....|..|.||.||||..|.| .|..|||.:...|. ...||.::|....::.:..:   |
  Fly  1667 QHRLKPDVDQFDPRYRLYAVVSHSG-MLNGGHYISYASNA-TGSWYCYNDSSCREISQKPV---I 1726

  Fly   908 INNEAYMLFYQRRSVD 923
            ..:.||:|||:|:.:|
  Fly  1727 DPSAAYLLFYERKGLD 1742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp15-31	NP_611959.2	UBP12	<255..921	CDD:227847	215/1033 (21%)
Usp32	NP_001262074.2	EFh_PI-PLC	198..>251	CDD:333715
		EF-hand motif	198..222	CDD:320029
		EF-hand_7	227..290	CDD:463900
		UBP12	486..>1002	CDD:227847	101/296 (34%)
		Peptidase_C19	<1480..1737	CDD:470612	67/266 (25%)