Protein Alignment Usp15-31 and Usp20

DIOPT Version :10

• Sequence 1: NP_611959.2
• Gene: Usp15-31 / 37954
• FlyBaseID: FBgn0050421
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: NP_001101297.1
• Gene: Usp20 / 311856
• RGDID: 1305621
• Length: 915
• Species: Rattus norvegicus
• Alignment Length: 719
• Identity: 161/719 - (22%)
• Similarity: 256/719 - (35%)
• Gaps: 228/719 - (31%)

  Fly   263 GVMGLKNHGNTCFMNAVLQCLSHTDILAEYFVLDQYKADLKRRNKINSRKFGTKGELTEQLANVL 327
            |:.|:||.||:|:|||.||.||:...|.::|:   ....|.|.:|        |..|.:....::
  Rat   143 GLTGMKNLGNSCYMNAALQALSNCPPLTQFFL---ECGGLVRTDK--------KPALCKSYQKLI 196

  Fly   328 KALWTCKNES-DHSTSFKAVVDRYGTQFRSSTQHDAQEFLFWLLDKVHEDLNTASKRRYKSLKNS 391
            ..:|..|..| ...||....:......||...|.|.||||..|:|::||:|
  Rat   197 SEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEEL-------------- 247

  Fly   392 YGRSDEVIAAETLANHIRCNNSFVQAVFQAQFRSSLTCPRCEKQSNTFDPF-HCISVQ------- 448
               .:.::||.......|.::|           |.....|...:|.:.|.| .|.|..
  Rat   248 ---KEPMVAAVAALTDARDSDS-----------SDTDERRDGDRSPSEDEFLSCDSSSDRGEGDG 298

  Fly   449 -----LPQLTQQTIFVTVVYMTRLPRQVRMGLRVPAGSPIVALREQLQADTGIEGSRMVLVDLNA 508
                 .....:..:.::......:..:.||..|..:........||:..|..::.:...|.:.:.
  Rat   299 QGRGGGSSKAEMELLISDEAGRAISEKERMKDRKFSWGQQRTNSEQVDEDADVDTAMASLDEQSR 363

  Fly   509 EGFTRVFYDTQPVETLSSIETIY-------CIEV-------------PAATPV--------AKAA 545
            |........|.|.:|......::       |..|             |.|:||        .||.
  Rat   364 EAQPPSPRPTSPCQTPEPDNEVHIRSSSRPCSPVHHHEGHTKLSSSPPRASPVRMGPSYVLKKAQ 428

  Fly   546 TPSETGDKSAPTAVTPSPAAAQSQADLLLLVANVYRAKDGADITRFGAPFSMKAPRDC------- 603
            .||..|.:             :.:.....::::|:.          |:..|:.....|
  Rat   429 VPSTGGRR-------------RKEQSYRSVISDVFN----------GSVLSLVQCLTCDRVSTTV 470

  Fly   604 -SYQDLQKRMLREMAPLLKPEVFSYATPLAEMFRIRLQDPSADP----DTYLEQVEHPLLTEMID 663
             ::|||.       .|:...|      .||::.....|:..|.|    |:|..|
  Rat   471 ETFQDLS-------LPIPGKE------DLAKLHSAIYQNVPAKPGACGDSYSSQ----------- 511

  Fly   664 MALSVLSSEAGPQHIKLLLEWSSPEAHFISKQQDTEEAVVEHESVARLSAS-KPS--DTAALTLE 725
                               .|.:              .:||:  :.|...| .||  ....:|||
  Rat   512 -------------------GWLA--------------FIVEY--IRRFVVSCTPSWFWGPVVTLE 541

  Fly   726 QCLEHYTKAETLSAEDAWRCPHCQQYLPVVKTLGLWSLPDILVVHFKRFRQHQSKGPQAAKLTTM 790
            .||..:..|:.|..::.:.|..|::....||...:..||:||.||.|||| |:..  .:.|:::.
  Rat   542 DCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLCLPEILCVHLKRFR-HEVM--YSFKVSSH 603

  Fly   791 VKFPLTAFDMSPHLARGVHESASSSLGMGTGIGLGLGLGSNPWKKARSVDSRSSTLNSRCDAKDT 855
            |.|||...|:.|.||:                                          .|.::.|
  Rat   604 VSFPLEGLDLRPFLAK------------------------------------------ECTSQVT 626

  Fly   856 RYDLYAVCYHQGDTLETGHYTAACKNPYDRQWYKFDDQRVSKVPEDDIEQDIINNEAYMLFYQRR 920
            .|||.:|..|.| |..:|||.|.|:|..:.|||:||||.|::|.|..::    |.|||:|||::.
  Rat   627 TYDLLSVICHHG-TAGSGHYIAYCQNVINGQWYEFDDQYVTEVHETVVQ----NVEAYVLFYRKS 686

  Fly   921 SVDA 924
            |.:|
  Rat   687 SEEA 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp15-31	NP_611959.2	UBP12	<255..921	CDD:227847	159/714 (22%)
Usp20	NP_001101297.1	zf-UBP	30..90	CDD:460464
		UCH	145..683	CDD:425685	156/708 (22%)
		DUSP	703..786	CDD:197831
		DUSP	811..895	CDD:197831