Protein Alignment Usp15-31 and Usp4

DIOPT Version :9

• Sequence 1: NP_611959.2
• Gene: Usp15-31 / 37954
• FlyBaseID: FBgn0050421
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: XP_006511759.1
• Gene: Usp4 / 22258
• MGIID: 98905
• Length: 967
• Species: Mus musculus
• Alignment Length: 968
• Identity: 264/968 - (27%)
• Similarity: 383/968 - (39%)
• Gaps: 275/968 - (28%)

  Fly    50 ADTSTTNAAKKIRRTFSMPRNPFRWTRKFKTAVAVTSSAGAENDNESGKNNGARERRGSHTAISS 114
            |||..| ..|::|:.|::|..  |.||.:...::.|....::.||..   ..|...:|....|..
Mouse   159 ADTIAT-IEKEMRKLFNIPAE--RETRLWNKYMSNTYEQLSKLDNTI---QDAGLYQGQVLVIEP 217

  Fly   115 CVGGGRGRSGSIVSLSSYEAPFISSTNNNTTTAS-----------NGNNNNSSSSNINSKRTRAL 168
            ....|.....|:.|.|| .||..:.|.::..:||           ||::.|||.
Mouse   218 QNEDGTWPRQSLQSKSS-TAPSRNFTTSSKPSASPYCSVSASLIANGDSTNSSG----------- 270

  Fly   169 RRSSFRKFLNRIAQHLSSTVNVVSEEKHSPANRIAFIEIVPFYTGCWRRKEANKHGQPSVSGSSS 233
                                      .||                               ||.|.
Mouse   271 --------------------------MHS-------------------------------SGVSR 278

  Fly   234 GGGGGAGGPGGGERVPPIGGYQWPADQTPGVMGLKNHGNTCFMNAVLQCLSHTDILAEYFVLDQY 298
            ||.|.:......|  ||....|      ||:.||.|.|||||||:.|||||:|..|.|||:.|:|
Mouse   279 GGSGFSASYNCQE--PPSPHIQ------PGLCGLGNLGNTCFMNSALQCLSNTAPLTEYFLKDEY 335

  Fly   299 KADLKRRNKINSRKFGTKGELTEQLANVLKALWTCKNESDHSTSFKAVVDRYGTQFRSSTQHDAQ 363
            :|::.|.|.:     |.|||:.|..|.::|.:|:.::.......||..|.|:..||....|.|:|
Mouse   336 EAEINRDNPL-----GMKGEIAEAYAELIKQMWSGRDTHVAPRMFKTQVGRFAPQFSGYQQQDSQ 395

  Fly   364 EFLFWLLDKVHEDLNTASKRRYKSLKNSYGRSDEVIAAETLANHIRCNNSFVQAVFQAQFRSSLT 428
            |.|.::||.:|||||...|:.|...|::.||.|.|:|.|...||...|:|.:...|...|:|:|.
Mouse   396 ELLAFILDGLHEDLNRVKKKPYLEPKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLV 460

  Fly   429 CPRCEKQSNTFDPFHCISVQLPQLTQQTIFVTVVYMTRLPRQVRMGLRVPAGSPIVALREQLQAD 493
            ||.|.|.|.|||||..:::.||....:.:.|.:|......|.::..:.||....|..|.|.|...
Mouse   461 CPECAKVSVTFDPFCYLTLPLPLKKDRIMEVFLVPADPQCRPIQYRVTVPLMGAISDLCEALSKL 525

  Fly   494 TGIEGSRMVLVDLNAEGFTRVFYDTQPVETLSSIETIYCIEVPAATPVAKAATPSETGDKSAPTA 558
            :||....||:.|:....|.::|...:.:..::..:.|:..||         ...|..|.:.....
Mouse   526 SGIAAENMVVTDVYNHRFHKIFQMDEGLSHITPRDDIFVYEV---------CNTSMDGSECITLP 581

  Fly   559 V-----TPSPAAAQSQADLLLLVANVYRAKDGADITRFGAPFSMKAPR-----DCSYQDLQKRML 613
            |     ...|::|.|.|.|                  :|.|..:..|:     :..||.:..|:.
Mouse   582 VYFREKKSRPSSASSGAVL------------------YGQPLLVSVPKHKLTLESLYQAVCDRIS 628

  Fly   614 REMAPLLKPEVFSYATPLAEMFRIRLQDPSA----------DPDTYLEQVEH-----PLLTEM-- 661
            |.:...|..|..|  :||         :|.|          |.:   |:::|     ..|:|:
Mouse   629 RYIKQPLPDEFLS--SPL---------EPGACNGSRSSYEGDEE---EEMDHQEEGKEQLSEVEG 679

  Fly   662 -------IDMALSVLSSEAGPQHIKLL--------------------------------LEWSSP 687
                   .|.:.|....:..|:|.:|.                                ::|.|.
Mouse   680 SGEDDQGDDHSESAQKVKGQPRHKRLFTFSLVNSCGTADINSLATDGKLLKLNSRSTLAIDWDSE 744

  Fly   688 EAHFISKQQDTE----EAVVEHESVARLSASKP--SDTAALTLEQCLEHYTKAETLSAEDAWRCP 746
            .......:|::|    :|..:|     ||.|:|  ...||:.|.:|:|.:|..|||...|.|.||
Mouse   745 TRSLYFDEQESECFSPQACEKH-----LSMSQPQKKKKAAVALRECIELFTTMETLGEHDPWYCP 804

  Fly   747 HCQQYLPVVKTLGLWSLPDILVVHFKRFRQHQSKGPQAAKLTTMVKFPLTAFDMSPHLARGVHES 811
            .|:::....|...|||||.|||||.|||..::.   ...||.|:|:||:.|.:||..:
Mouse   805 TCKKHQQATKKFDLWSLPKILVVHLKRFSYNRY---WRDKLDTVVEFPVRALNMSEFV------- 859

  Fly   812 ASSSLGMGTGIGLGLGLGSNPWKKARSVDSRSSTLNSRCD--AKDTRYDLYAVCYHQGDTLETGH 874
                                                  ||  |:...|||.||..|.| .:..||
Mouse   860 --------------------------------------CDRSARPYVYDLIAVSNHYG-AMGVGH 885

  Fly   875 YTAACKNPYDRQWYKFDDQRVSKVPEDDIEQDIINNEAYMLFYQRRSVDAGECSGSSS 932
            |||..||..:.:||.|||..||...||    .|:...||:||||||.   .|||.:||
Mouse   886 YTAYAKNRLNGKWYYFDDSSVSLASED----QIVTKAAYVLFYQRRD---DECSSTSS 936

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp15-31	NP_611959.2	Peptidase_C19	<262..>383	CDD:271592	53/120 (44%)
		Peptidase_C19	266..>461	CDD:271592	81/194 (42%)
		Peptidase_C19R	<713..918	CDD:239139	70/208 (34%)
Usp4	XP_006511759.1	UBP12	35..927	CDD:227847	257/954 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5560
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1283205at2759
OrthoFinder	1	1.000	-	-		FOG0000596
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820