Protein Alignment Usp15-31 and usp43

DIOPT Version :10

• Sequence 1: NP_611959.2
• Gene: Usp15-31 / 37954
• FlyBaseID: FBgn0050421
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: XP_031750350.1
• Gene: usp43 / 101734180
• XenbaseID: XB-GENE-940625
• Length: 1135
• Species: Xenopus tropicalis
• Alignment Length: 1125
• Identity: 361/1125 - (32%)
• Similarity: 532/1125 - (47%)
• Gaps: 199/1125 - (17%)

  Fly   164 RTRALRRSSFRKFLNRIAQ---HLSSTVNVVSEEKHSPANRIAFIEIVPFYTGCWRRKEANKHGQ 225
            |:|:|:  |...|::||.:   |||.    |.|..|.....         ..|.:.||...:...
 Frog    16 RSRSLK--SVGDFVHRILRTISHLSH----VGEASHEDGEE---------DDGGFSRKATAQEDW 65

  Fly   226 PSVSGSSSGGGGGAGGPGGGERVPPIGGYQWPA-DQTPGVMGLKNHGNTCFMNAVLQCLSHTDIL 289
            ..|.|..|....|.....|.:||      .|.: |:.|||.|:||||||||||||:||||:||:|
 Frog    66 RVVHGGDSNNNLGKVQASGQDRV------SWSSDDKVPGVQGMKNHGNTCFMNAVVQCLSNTDML 124

  Fly   290 AEYFVLDQYKADLKRRNKIN-----------SRKFGTKGELTEQLANVLKALWTCKNESDHSTSF 343
            ||:..:::|||.|. :.|:|           :......||:||:||::::.|||.:.....|..|
 Frog   125 AEFLGMERYKAQLS-KGKVNGVLVREAEGPPTGGASGSGEVTERLASLVRGLWTLEYTPHLSAEF 188

  Fly   344 KAVVDRYGTQFRSSTQHDAQEFLFWLLDKVHEDLNTASKRRYKSLKNSYGRSDEVIAAETLANHI 408
            |.||.:||||||.::||||.|||.||||:||||||....::.|:  .:....::|:.::  :...
 Frog   189 KNVVSKYGTQFRGNSQHDALEFLLWLLDRVHEDLNATCGQKAKA--KAGAEQNQVVHSQ--SPEP 249

  Fly   409 RCNNSFVQAVFQAQFRSSLTCPRCEKQSNTFDPFHCISVQLPQLTQQTIFVTVVYMTRLPRQVRM 473
            ..:.||||..||||:|||||||.|.:||:|||||.|:|:.||....:.:.:|:|:.|:..|.||:
 Frog   250 GGSQSFVQEHFQAQYRSSLTCPHCHRQSDTFDPFLCVSLPLPLRQTRALNLTLVFQTKQQRFVRV 314

  Fly   474 GLRVPAGSPIVALREQLQADTGIEGSRMVLVDLNAEGFTRVFYDTQPVETLSSIETIYCIEVPAA 538
            ||.||....:.:||:.:..:..:...:::||:|...||.|.|.|.:.:.:::..:.:|..:.|
 Frog   315 GLAVPLLGTVTSLRKMVADEGNMAPDQVILVELYPSGFQRSFSDDEDLNSIAEGDPVYAFQAP-- 377

  Fly   539 TPVAKAATPSE-TG-DKSAPTAVT-PSPAA----------AQSQAD---LLLLVANVYRAKDGAD 587
            .|:.||:.||. || .:|.|::.. |.|.|          ::..||   :|||:.|.  ...|..
 Frog   378 VPIPKASGPSRPTGYPRSLPSSPRYPDPEAQKFSGAGSKSSEFLADPDRILLLLCNT--EGSGKQ 440

  Fly   588 ITRFGAPFSMKAPRDCSYQDLQKRMLREMAPLLKPEVFSYATPLAEMFRIRLQDPSADPDTYLEQ 652
            ..|||.|..::.....|::.||:.:|.::..||:.|........| :|.||:....|. .:||..
 Frog   441 ANRFGPPLLVREDSTLSWEQLQQCILGKLRYLLRNEALLQQNGTA-LFHIRVVGGPAS-GSYLSP 503

  Fly   653 VE-HPLLTEMIDMALSVLSSEAGPQHIKLLLEW--SSPEAHFISKQQDTEEAVVEHESVARLSAS 714
            .: .||....|:.||. ||...||.|:||.:||  .:.|..|.:.|   ||.|.:.|||......
 Frog   504 KDPRPLQHPAIERALQ-LSGAGGPPHVKLAIEWEPKTKERLFGNIQ---EEVVHDDESVRAQQLE 564

  Fly   715 KPSDTAALTLEQCLEHYTKAETLSAEDAWRCPHCQQYLPVVKTLGLWSLPDILVVHFKRFRQHQS 779
            ....:.  ||::|.:.|||.|.|:.:||||||:|:........|.||:|||||::|.|||||
 Frog   565 HQQQSC--TLDECFQLYTKEEQLAPDDAWRCPYCKVLQQGTVKLSLWTLPDILIIHLKRFRQ--- 624

  Fly   780 KGPQAAKLTTMVKFPLTAFDMSPHLARGVHESASSSLGMGTGIGLGLGLGSNPWKKARSVDSRSS 844
            .|.:..||:|:|:|||...||:||:.:       .|.| |.|:   ||..:: ||.|...:.:
 Frog   625 VGGRRNKLSTLVRFPLAGLDMAPHVVK-------RSQG-GKGM---LGQWAS-WKNAPMENGQ-- 675

  Fly   845 TLNSRCDAKDTRYDLYAVCYHQGDTLETGHYTAACKNPYDRQWYKFDDQRVSKVPEDDIEQDIIN 909
                    .|..|||||||.|.| :|:.|||||.|:|..|.:||.:||..|..|.    |.|:..
 Frog   676 --------LDVHYDLYAVCNHHG-SLQGGHYTAYCRNSLDARWYSYDDSNVEHVQ----ETDVCT 727

  Fly   910 NEAYMLFYQRRSV-----DAGECSGSSSNS-GDHWVSRIAPASSSSASSTSGKEREPVKLEENT- 967
            ..||:||||:|:.     .:....||:|:| .|||:.|:           :|..||.:.....|
 Frog   728 RGAYLLFYQKRNAIPMWSASSSVRGSTSSSVSDHWILRL-----------NGSRRESLASRATTN 781

  Fly   968 --------ESPAAVEVTE---KAQSKPVDIVCQDKAKG------TADGPDADQEQTTVPHDLQIE 1015
                    :||..:|..|   |..|||.       |:|      :...|.|.:.:.::...:
 Frog   782 CFNRIQPPDSPVFLEKEEHPDKGGSKPF-------ARGIKGRSASMKLPSASKLKLSISKAM--- 836

  Fly  1016 ELAFADADVDTSLGETIKAEVNLAAKDEPKKVEVEEATPIFAMDEDGSEARQEKKEECVKKEDEL 1080
            .|.::....|.:..||.:....|.:...||... |...|:.|     .....||:|:..|
 Frog   837 PLRWSFGSKDRTKRETGQLVEYLESGRRPKYTN-EPIVPLMA-----GLPTTEKEEQQAK----- 890

  Fly  1081 SEAPDVSELTAESKTNGHVSSSSSSSSS--------ESSL--------SSRSSPRSLSTSVTAAS 1129
            :..|....:.....|:....||||...|        ||:|        |:....|...::|..||
 Frog   891 ANLPKTQGVNGAGGTSKPTPSSSSRLDSQRGRPKERESTLNATQTGVGSAMPKEREARSAVDCAS 955

  Fly  1130 TLQSKFNGHMSAAPALFNGNGNTSQLSSSLQLSRHVLHNHQWHGSRSSVSAVENATQ-------- 1186
            .:.|...|:....|.|....|.:||        |:|:.|    ||...|...|...|
 Frog   956 GMSSLDLGNGLKGPVLLAKKGESSQ--------RNVIKN----GSNPRVKPSEAEGQPINVKPNT 1008

  Fly  1187 -----HQQQQAAASLSLRHS 1201
                 .:|.....|..|.||
 Frog  1009 VKKEIRRQSGTENSSGLEHS 1028

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp15-31	NP_611959.2	UBP12	<255..921	CDD:227847	264/696 (38%)
usp43	XP_031750350.1	UBP12	<58..739	CDD:227847	272/733 (37%)