Protein Alignment Usp15-31 and usp2

DIOPT Version :10

• Sequence 1: NP_611959.2
• Gene: Usp15-31 / 37954
• FlyBaseID: FBgn0050421
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: XP_012821651.1
• Gene: usp2 / 100216064
• XenbaseID: XB-GENE-962796
• Length: 564
• Species: Xenopus tropicalis
• Alignment Length: 904
• Identity: 180/904 - (19%)
• Similarity: 274/904 - (30%)
• Gaps: 394/904 - (43%)

  Fly    75 TRKFKTAVAVTSSAGAENDNESGKNNGARERRGSHTAISSCVGGGRGRSGSIVSLSSY-----EA 134
            |.|..|..:.|.|.|:.:...|..|:...:|    ..|......|.....|...|.||     ..
 Frog     7 TLKRYTDTSYTKSYGSFSSYTSNLNSSYIDR----DKIPYKTSFGSSYLSSSPHLRSYPELERSL 67

  Fly   135 PFISSTNNNT-----TTASNGNNN--------NSSSSNINSKRTRAL--RRSSFRKFLNRIAQHL 184
            |.:..|:..|     :|:..|.:|        |::.|.|.:....:|  |:||....|:.....|
 Frog    68 PRLDVTSKRTDIVGRSTSKYGTSNFPTYSYGYNTTYSPITASPVTSLTRRKSSSHTDLSHGLSEL 132

  Fly   185 SSTVNVVSEEKHSPANRIAFIEIVPFYTGCWR-RKEANKHGQPSVSGSSSGGGGGAG-------- 240
            .::....|.   |||...:.:|.    .|.:| .:..|......:.|...|...|.|
 Frog   133 RASDTYYSP---SPALTCSRLEA----DGNYRVSRTTNLSDVSDIYGKKRGSTNGYGISRTTVQD 190

  Fly   241 ----GPGGGERVPPIGGYQWPADQTP------------GVMGLKNHGNTCFMNAVLQCLSHTDIL 289
                .|....|..    |.:...:.|            |::||:|.|||||||::|||||:|..|
 Frog   191 PAPSSPKSNTRFL----YSYDKKEEPSSKEEKSSKHVQGLVGLRNLGNTCFMNSILQCLSNTKDL 251

  Fly   290 AEYFVLDQYKADLKRRNKINSRKFGTKGELTEQLANVLKALWTCK-NESDHSTSFKAVVDRYGTQ 353
            .:|.:.:.|:.||      :|:|..|  .:.|:.|.:|:|:||.. ||....:.||..:.:|..:
 Frog   252 RDYCLQNSYRRDL------SSKKCNT--AIMEEFARLLQAIWTSSANEVVSPSEFKTQIQKYAPR 308

  Fly   354 FRSSTQHDAQEFLFWLLDKVHEDLNTASKRRYKSLKNSYGRSDEVIAAETLANHIRCNNSFVQAV 418
            |....|.||||||.:|||.:|.::|..:.:...|.::.....|..........::...:|.:..:
 Frog   309 FMGYNQQDAQEFLRFLLDGLHNEVNRVTVKPRPSSQDLDHMPDSEKGKHMWKRYLEREDSRIVEL 373

  Fly   419 FQAQFRSSLTCPRCEKQSNTFDPFHCISVQLPQLTQQTIFVTVVYMTRLPRQVRMGLRVPAGSPI 483
            |..|.:|||||..|...|..||||..:|:
 Frog   374 FVGQLKSSLTCTECGYCSTVFDPFWDLSL------------------------------------ 402

  Fly   484 VALREQLQADTGIEGSRMVLVDLNAEGFTRVFYDTQPVETLSSIETIYCIEVPAATPVAKAATPS 548
                                                                    |:||
 Frog   403 --------------------------------------------------------PIAK----- 406

  Fly   549 ETGDKSAPTAVTPSPAAAQSQADLLLLVANVYRAKDGADITRFGAPFSMKAPRDCSYQDLQKRML 613
                |||
 Frog   407 ----KSA---------------------------------------------------------- 409

  Fly   614 REMAPLLKPEVFSYATPLAEMFRIRLQDPSADPDTYLEQVEHPLLTEMIDMALSVLSSEAGPQHI 678
                                                                             
 Frog   410 ----------------------------------------------------------------- 409

  Fly   679 KLLLEWSSPEAHFISKQQDTEEAVVEHESVARLSASKPSDTAALTLEQCLEHYTKAETLSAEDAW 743
                                                     :.::|..|:..:||.:.|..::..
 Frog   410 -----------------------------------------SEVSLVDCMRLFTKEDVLDGDEKP 433

  Fly   744 RCPHCQQYLPVVKTLGLWSLPDILVVHFKRFRQHQSKGPQAAKLTTMVKFPLTAFDMSPHLARGV 808
            .|..|:......|...:...|.|||:|.|||.:.:.:   :.||:|.|.|||...|:
 Frog   434 TCCRCKARRRCTKKFTIQKFPKILVLHLKRFSEGRIR---SGKLSTFVNFPLKDLDL-------- 487

  Fly   809 HESASSSLGMGTGIGLGLGLGSNPWKKARSVDSRSSTLNSRCDAKDTRYDLYAVCYHQGDTLETG 873
            .|.:|.               |||                     ...|:||||..|.|.|: .|
 Frog   488 REFSSE---------------SNP---------------------HATYNLYAVSNHSGTTM-GG 515

  Fly   874 HYTAACKNPYDRQWYKFDDQRVSKVPEDDIEQDIINNEAYMLFYQRRSVDAGECSGSSS 932
            ||||.||||.:.:||.|:|.||:.:..:.:.    :::||:|||        |.||.||
 Frog   516 HYTAYCKNPSNGEWYTFNDSRVTAMSSNQVR----SSDAYVLFY--------ELSGPSS 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp15-31	NP_611959.2	UBP12	<255..921	CDD:227847	130/678 (19%)
usp2	XP_012821651.1	UCH	227..555	CDD:425685	126/652 (19%)