Protein Alignment Usp15-31 and Usp43

DIOPT Version :10

• Sequence 1: NP_611959.2
• Gene: Usp15-31 / 37954
• FlyBaseID: FBgn0050421
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: XP_038940907.1
• Gene: Usp43 / 100147704
• RGDID: 2303824
• Length: 1136
• Species: Rattus norvegicus
• Alignment Length: 1128
• Identity: 359/1128 - (31%)
• Similarity: 515/1128 - (45%)
• Gaps: 223/1128 - (19%)

  Fly   166 RALRRSSFRKFLNRIAQHLSSTVNVVSEEKHSPANRIAFIEIVPFYTGCWRRKEANKHGQPS-VS 229
            |..||.|.|:.|||....|.|..........:||                         ||| ..
  Rat    17 RPRRRRSLRRLLNRFLLALVSRSRSGDSPPRAPA-------------------------QPSPYD 56

  Fly   230 GSSSGGGGGAGGPG-------GGERVPPIGGY----QWPADQTPGVMGLKNHGNTCFMNAVLQCL 283
            |...||...|.||.       |.:|  |:|..    .....:.||..||||||||||||||:|||
  Rat    57 GDGEGGFACAPGPAPASSGSPGPDR--PLGSQPQISSGDGARPPGAQGLKNHGNTCFMNAVVQCL 119

  Fly   284 SHTDILAEYFVLDQYKADLKRRNKINSRKFGTKGELTEQLANVLKALWTCKNESDHSTSFKAVVD 348
            |:||:|||:..|.:|:|            ...:.|:|||||.:::||||.:.....|..||..|.
  Rat   120 SNTDLLAEFLALGRYRA------------VPGRAEVTEQLAALVRALWTREYTPQLSAEFKNAVS 172

  Fly   349 RYGTQFRSSTQHDAQEFLFWLLDKVHEDLNTASKRRYKSLKNSYGRSDEVIAAET--LANHIRCN 411
            :||:||:.::||||.|||.||||:|||||.          .:::|:..|.:..|.  ::..:|.:
  Rat   173 KYGSQFQGNSQHDALEFLLWLLDRVHEDLE----------GSTHGQGSEQLPPEASKISEDLRSS 227

  Fly   412 -------NSFVQAVFQAQFRSSLTCPRCEKQSNTFDPFHCISVQLPQLTQQTIFVTVVYMTRLPR 469
                   .||||:.||||:|||||||.|.|||||||||.|:|:.:|....:.:.||:|:.::..|
  Rat   228 AAPPSLGPSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQR 292

  Fly   470 QVRMGLRVPAGSPIVALREQLQADTGIEGSRMVLVDLNAEGFTRVFYDTQPVETLSSIETIYCIE 534
            .:|:||.||..|.:.|||:.:..:.|:....::||:|...||.|.|:|.:.:.|::..:.:|..:
  Rat   293 FLRVGLAVPILSTVAALRKMVAEEGGVPAEEVILVELYPNGFQRSFFDEEDLNTIAEGDNVYAFQ 357

  Fly   535 VPAATPVAKAATPSETGDKSAPTAVTPSPAAA-----------QSQADLLLLVANVYRAKDGADI 588
            ||   |:....|.:     :.|..::.||..|           .|:..:|:|..|:  ...|...
  Rat   358 VP---PLPGPGTLA-----AHPPGLSVSPRLAVRDSQRFSVPLHSENRVLILFCNL--VGSGQQA 412

  Fly   589 TRFGAPFSMKAPRDCSYQDLQKRMLREMAPLLKPEVFSYATPLAEMFRIRLQDPSADPDTYLEQV 653
            :|||.||.::..|..|:..||:.:|.::..|::.||  .|..|..:|.||:...|........|.
  Rat   413 SRFGPPFLIREDRTISWAQLQQCILSKVRCLMRNEV--SAQDLGTLFSIRVVGLSLACSYLSPQD 475

  Fly   654 EHPLLTEMIDMALSVLSSEAGPQHIKLLLEWSS--PEAHFISKQQDTEEAVVEHESVARLSAS-- 714
            ..||....:|.||. |....||.|:||.:||.|  .|..|.|.|   ||.|.:.:||.|...:
  Rat   476 SRPLCHWAVDRALH-LRRPGGPPHVKLAVEWDSSVTERLFGSLQ---EERVQDADSVWRQQQAHQ 536

  Fly   715 KPSDTAALTLEQCLEHYTKAETLSAEDAWRCPHCQQYLPVVKTLGLWSLPDILVVHFKRFRQHQS 779
            :||    .||::|.:.|||.|.|:.:|||:|||||.....|..|.||:|||||::|.|||.|
  Rat   537 QPS----CTLDECFQSYTKEEQLAQDDAWKCPHCQVLQQGVVKLSLWTLPDILIIHLKRFCQ--- 594

  Fly   780 KGPQAAKLTTMVKFPLTAFDMSPHLARGVHESASSSLGMGTGIGLGLGLGSNPWKKARSVDSRSS 844
            .|.:..||:|:|||||:..:|:||:||   .|.:|..|.|            ||...:......:
  Rat   595 VGERRNKLSTLVKFPLSGLNMAPHVAR---RSTNSKAGPG------------PWSSWKQPICLPT 644

  Fly   845 TLNSRCDAKDTRYDLYAVCYHQGDTLETGHYTAACKNPYDRQWYKFDDQRVSKVPEDDIEQDIIN 909
            |.     ..|..|||||||.|.| :|:.|||||.|:|..|.|||.:||..|..:.||::.    .
  Rat   645 TY-----PLDFLYDLYAVCNHHG-SLQGGHYTAYCRNSLDGQWYSYDDSTVEPLREDEVN----T 699

  Fly   910 NEAYMLFYQRR-SVDAGECSGS-----SSNSGDHWVSRIAPASSSSASSTSGKEREPVKLEENTE 968
            ..||:||||:| |:.....|.|     ||:..|||:.|:...::|:..|.......|
  Rat   700 RGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLMRLGSLNNSTRGSLMSWSSAP-------- 756

  Fly   969 SPAAVEVTEKAQSKPV--DIVCQDKAKGTADGP-----DADQEQTTVPHDLQIEELAFADADVDT 1026
            .|:...|.:    .||  :.||| :.||...||     ........||...:.....|....:..
  Rat   757 CPSVARVPD----SPVFTNGVCQ-QDKGVEAGPLVQGVGGRSISMKVPPTSRSRHGPFKTMPLRW 816

  Fly  1027 SLGETIK---AEVNLA----AKDEPKKVEVEEATPIFAMDEDGSEARQEKKEECVKKEDELSEAP 1084
            |.|...|   |.|.|.    ::..|:... :...|:......|               ||.|.:|
  Rat   817 SFGHREKRPGASVELVEYLESRRRPRSTS-QSIVPLLTRAAGG---------------DETSASP 865

  Fly  1085 -DVSELTAESKTNGHVSSSSSSSSSESS--LSSRSSPRSLSTSVTAAST----------LQSKFN 1136
             ..:.|.|:|..:|..:...::....||  |:..|:..||...:..|.|          |..||:
  Rat   866 RSDATLPAKSDNSGRATGQGTNGVPLSSCHLNHHSALGSLDDGLHTARTRTGNASQDIRLPKKFD 930

  Fly  1137 GHMSAAPALFNGNGNTSQLSSSLQLSRHVLHNHQ----WHGSRSSVSAVENATQHQQQQAAASLS 1197
            ..::..|:..:|              :|.....|    |.|| |.|.:       |....:.|..
  Rat   931 LPLTVMPSAEDG--------------KHARPEGQKMTTWKGS-SQVGS-------QSSPPSPSTG 973

  Fly  1198 LRHSFSTSSNYTETLSSLLRKSA 1220
            |..:|  ..|...||..:..|:|
  Rat   974 LLRNF--KDNGLGTLPKMKAKAA 994

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp15-31	NP_611959.2	UBP12	<255..921	CDD:227847	262/690 (38%)
Usp43	XP_038940907.1	UBP12	<77..711	CDD:227847	265/705 (38%)