Protein Alignment SiaT and ST6GAL2

DIOPT Version :9

• Sequence 1: NP_523853.1
• Gene: SiaT / 37950
• FlyBaseID: FBgn0035050
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001135823.1
• Gene: ST6GAL2 / 84620
• HGNCID: 10861
• Length: 529
• Species: Homo sapiens
• Alignment Length: 451
• Identity: 140/451 - (31%)
• Similarity: 213/451 - (47%)
• Gaps: 93/451 - (20%)

  Fly    33 HIQGVKAQPGREPGEVNSRQPGNGAYENSTGTERRLRK---------VIWKCIPTGNGTTGHR-- 86
            |.||....|  .|||...|:   ||:..:....||::|         |:      ..|..|.|
Human   143 HTQGTLGFP--SPGEPGPRE---GAFPAAQVQRRRVKKRHRRQRRSHVL------EEGDDGDRLY 196

  Fly    87 --VPRSVFHVRWNPNEKFIVESRENPAINSSKLAPHPRLKVSKNTKLTLSPKLYLCHDKHSELCH 149
              :.|:..:..|..|.             |||:.         |.:|..:.|.||..:||.
Human   197 SSMSRAFLYRLWKGNV-------------SSKML---------NPRLQKAMKDYLTANKHG---- 235

  Fly   150 NKTQQFRQRIVRAFEKAMVESVNESQANHYNVDYKPVFGDSFEEQYYPSTCLVMEAGVRVLRRKD 214
               .:||.:......:|.:.....|:|.                             ||.|...:
Human   236 ---VRFRGKREAGLSRAQLLCQLRSRAR-----------------------------VRTLDGTE 268

  Fly   215 APFNKLPFGRLFPRQKLFR-NVKDIKTCAIVSSAGSLAGSKLGRFIDTHDIVMRFNHAPTQGHEV 278
            |||:.|.:.||.|...|.: :.:.:::||:|.|||::..|.||..||:||.|:|||.|||:|:|.
Human   269 APFSALGWRRLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEK 333

  Fly   279 DVGSKTTIRVVNSQVVTKPEFDFTRAPIFRNVTIAAWDPGKYNGTLEDWLTSADYDLFSNYELYR 343
            |||:|||||::|||::|.|...|..:.::::|.:.||||..|:..|..|....||:||:.|..:|
Human   334 DVGNKTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHR 398

  Fly   344 RRYPKSRAFLIDPHSVWRLWQSLQMFAGNRPISKNPPSSGFIGLALLLPHCPQVDFVEYVPSTRL 408
            :|.|....:::.|..:|:||..:|.....: |..|||||||||:.:::..|.:|...||:||.|.
Human   399 QRNPNQPFYILHPKFIWQLWDIIQENTKEK-IQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQ 462

  Fly   409 NGRCHYYSKEMNSACTFGSWHPLAAEKLMALDMNMAEDDDMSVFQFGILRIRRPDKLLCGF 469
            ...|||:....::|||.|::|||..|||:...:||....|:.         |:...:|.||
Human   463 TELCHYHELYYDAACTLGAYHPLLYEKLLVQRLNMGTQGDLH---------RKGKVVLPGF 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SiaT	NP_523853.1	Glyco_transf_29	224..437	CDD:279159	90/213 (42%)
ST6GAL2	NP_001135823.1	Glyco_transf_29	278..511	CDD:279159	95/242 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	200	1.000	Domainoid score	I3039
eggNOG	1	0.900	-	-		E1_KOG2692
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3770
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D231534at33208
OrthoFinder	1	1.000	-	-		FOG0002913
OrthoInspector	1	1.000	-	-		otm40867
orthoMCL	1	0.900	-	-		OOG6_109878
Panther	1	1.100	-	-	O	PTHR46059
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5281
SonicParanoid	1	1.000	-	-		X1922
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.860