DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SiaT and ST6GALNAC5

DIOPT Version :9

Sequence 1:	NP_523853.1	Gene:	SiaT / 37950	FlyBaseID:	FBgn0035050	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_112227.1	Gene:	ST6GALNAC5 / 81849	HGNCID:	19342	Length:	336	Species:	Homo sapiens

Alignment Length:	238	Identity:	60/238 - (25%)
Similarity:	101/238 - (42%)	Gaps:	37/238 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 KTCAIVSSAGSLAGSKLGRFIDTHDIVMRFNHAPTQGHEVDVGSKTTIRVV---NSQVVTKPEFD 300
            :.||:|:|:|.|..|:.|..||..:.|:|.|.|||:|:..|||::|::||:   :.|.:.:...|
Human    94 RDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRNRHD 158

  Fly   301 FTRAPIFRNVTIAAWDPGKYNGTLEDWLTSADYDLFSNYELYRRRYPKSRAFLIDPHSVWRLWQS 365
            ...  :.:......|.|..|      ........:::|..|..:..|:.:||:|..|.:.:..:.
Human   159 LLN--VSQGTVFIFWGPSSY------MRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKMLQFDEL 215

  Fly   366 LQMFAG-NRPISKNPPSSGFIGLALLLPHCPQVDFVEYVPSTRLNGRC----------HYYSKEM 419
            .:...| :|.||....|:|:..:.:.|..|.:::....||.    ..|          |||....
Human   216 FKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPP----DFCRDPNHPSVPYHYYEPFG 276

  Fly   420 NSACTF---------GSWHPLAAEKLMALDMNMAEDDDMSVFQ 453
            ...||.         ||.|....||  .:..|.|...::..||
Human   277 PDECTMYLSHERGRKGSHHRFITEK--RVFKNWARTFNIHFFQ 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SiaT	NP_523853.1	Glyco_transf_29	224..437	CDD:279159	56/220 (25%)
ST6GALNAC5	NP_112227.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	32..81
ST6GALNAC5	NP_112227.1	Glyco_transf_29	92..275	CDD:307084	49/192 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2692
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.770