Protein Alignment SiaT and ST8SIA1

DIOPT Version :9

• Sequence 1: NP_523853.1
• Gene: SiaT / 37950
• FlyBaseID: FBgn0035050
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_003025.1
• Gene: ST8SIA1 / 6489
• HGNCID: 10869
• Length: 356
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 65/264 - (24%)
• Similarity: 103/264 - (39%)
• Gaps: 72/264 - (27%)

  Fly   225 LFPRQKLFRNVKDIKTCAIVSSAGSLAGSKLGRFIDTHDIVMRFNHAP-TQGHEVDVGSKTTIRV 288
            |||:...|:  ..:|.||:|.:.|.|..|..||.||..:.|||.|..| :..:..|||||:.:..
Human   124 LFPQATPFQ--LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVT 186

  Fly   289 VNSQVVTKPEFD---FTRAPIFRNVTIAAWDPGKYN-------------GT---LEDWLTSADYD 334
            .|..:: :..|.   ::|.....|:.|       ||             ||   |..:.|.:|..
Human   187 ANPSII-RQRFQNLLWSRKTFVDNMKI-------YNHSYIYMPAFSMKTGTEPSLRVYYTLSDVG 243

  Fly   335 -----LFSNYELYRRRYPKSRAFLIDPHSVWRLWQSLQMFAGNRPISKNPPSSGFIGLALLLPHC 394
                 ||:|....|              |:.:.|:|       |.|.....|:|...::..|..|
Human   244 ANQTVLFANPNFLR--------------SIGKFWKS-------RGIHAKRLSTGLFLVSAALGLC 287

  Fly   395 PQVDFVEYVP-STRLNGR---CHYYSKEMNSACTFGSWHPLAAE--------KLMALDMNMAEDD 447
            .:|....:.| |..::.:   .|||    ::...|..:|.:..|        |:.||.|.:...:
Human   288 EEVAIYGFWPFSVNMHEQPISHHYY----DNVLPFSGFHAMPEEFLQLWYLHKIGALRMQLDPCE 348

  Fly   448 DMSV 451
            |.|:
Human   349 DTSL 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SiaT	NP_523853.1	Glyco_transf_29	224..437	CDD:279159	60/248 (24%)
ST8SIA1	NP_003025.1	Glyco_transf_29	92..344	CDD:366297	63/254 (25%)
		Substrate binding. /evidence=ECO:0000250|UniProtKB:O43173	188..190		1/1 (100%)
		Substrate binding. /evidence=ECO:0000250|UniProtKB:O43173	274..276		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2692
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810