Protein Alignment SiaT and ST3GAL1

DIOPT Version :10

• Sequence 1: NP_523853.1
• Gene: SiaT / 37950
• FlyBaseID: FBgn0035050
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_003024.1
• Gene: ST3GAL1 / 6482
• HGNCID: 10862
• Length: 340
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 71/331 - (21%)
• Similarity: 123/331 - (37%)
• Gaps: 92/331 - (27%)

  Fly   123 LKVSKNTKLTLSPKLYLC-----HDKHSELCHNKTQQFRQRIVRAFEKAMVES---------VNE 173
            |::|:|.|..:..:...|     ..|.|.....:..|..|.::.| :.|::|.         ..|
Human    44 LELSENLKRLIKHRPCTCTHCIGQRKLSAWFDERFNQTMQPLLTA-QNALLEDDTYRWWLRLQRE 107

  Fly   174 SQANHYNVDYKPVFGDSFEEQYYPSTCLVMEAGVRVLRRKDAPFNKLPFGRLFPRQKLFRNVKDI 238
            .:.|:.|...|.:|                    ||:     |.|..|.        |.:.....
Human   108 KKPNNLNDTIKELF--------------------RVV-----PGNVDPM--------LEKRSVGC 139

  Fly   239 KTCAIVSSAGSLAGSKLGRFIDTHDIVMRFNHAPTQGHEVDVGSKTTIRVV----------NSQV 293
            :.||:|.::|:|..|..|..||:||.|:|.|.|||.|.|.|||:|||..:|          |..:
Human   140 RRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVSM 204

  Fly   294 VTKPEFDFTRAPIFRNVTIAAWDPGKYNGTLEDWLTSA-DYDLFSNYEL---YRRRYPKSRAFLI 354
            :..|         |:.:.:             :|:.|| .....|:..:   .:.|..:.:..:.
Human   205 ILVP---------FKTIDL-------------EWVVSAITTGTISHTYIPVPAKIRVKQDKILIY 247

  Fly   355 DPHSVWRLWQSLQMFAGNRPISKNPPSSGFIGLALLLPHCPQVDFVEYVPSTRLNGRCHYYSKEM 419
            .|..:..::.:.....|..      ||:|.:.:...:..|.:||...:...::  |..|:|.:..
Human   248 HPAFIKYVFDNWLQGHGRY------PSTGILSVIFSMHVCDEVDLYGFGADSK--GNWHHYWENN 304

  Fly   420 NSACTF 425
            .||..|
Human   305 PSAGAF 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SiaT	NP_523853.1	GT29_ST6GAL1_2	199..469	CDD:467696	54/241 (22%)
ST3GAL1	NP_003024.1	GT29_ST3GAL1	59..338	CDD:467708	67/316 (21%)