Protein Alignment SiaT and ST6GAL1

DIOPT Version :9

• Sequence 1: NP_523853.1
• Gene: SiaT / 37950
• FlyBaseID: FBgn0035050
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001340845.1
• Gene: ST6GAL1 / 6480
• HGNCID: 10860
• Length: 406
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 107/280 - (38%)
• Similarity: 155/280 - (55%)
• Gaps: 6/280 - (2%)

  Fly   172 NESQANHYNVDYK-PVFGDSFEEQYYPSTCLVME-AGVRVLRRKDAPFNKLPFGRLFPRQKLFRN 234
            |....|.|.|.|| |..|..|..:  ...|.:.: ..|.::...|.|||...:....|::.:...
Human   115 NYLSMNKYKVSYKGPGPGIKFSAE--ALRCHLRDHVNVSMVEVTDFPFNTSEWEGYLPKESIRTK 177

  Fly   235 VKDIKTCAIVSSAGSLAGSKLGRFIDTHDIVMRFNHAPTQGHEVDVGSKTTIRVVNSQVVTKPEF 299
            ......||:|||||||..|:|||.||.||.|:|||.|||...:.|||:|||||::|||:|| .|.
Human   178 AGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVT-TEK 241

  Fly   300 DFTRAPIFRNVTIAAWDPGKYNGTLEDWLTSADYDLFSNYELYRRRYPKSRAFLIDPHSVWRLWQ 364
            .|.:..::....:..|||..|:..:..|..:.||:.|:||:.||:.:|....:::.|...|.||.
Human   242 RFLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWD 306

  Fly   365 SLQMFAGNRPISKNPPSSGFIGLALLLPHCPQVDFVEYVPSTRLNGRCHYYSKEMNSACTFGSWH 429
            .||..:... |..||||||.:|:.:::..|.|||..|::||.|....|:||.|..:||||.|::|
Human   307 ILQEISPEE-IQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFDSACTMGAYH 370

  Fly   430 PLAAEKLMALDMNMAEDDDM 449
            ||..||.:...:|...|:|:
Human   371 PLLYEKNLVKHLNQGTDEDI 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SiaT	NP_523853.1	Glyco_transf_29	224..437	CDD:279159	89/212 (42%)
ST6GAL1	NP_001340845.1	Glyco_transf_29	169..384	CDD:307084	89/216 (41%)
		Substrate binding. /evidence=ECO:0000269|PubMed:23999306, ECO:0007744|PDB:4JS1	322..324		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	200	1.000	Domainoid score	I3039
eggNOG	1	0.900	-	-		E1_KOG2692
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3770
Isobase	1	0.950	-	0	Normalized mean entropy	S7453
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D231534at33208
OrthoFinder	1	1.000	-	-		FOG0002913
OrthoInspector	1	1.000	-	-		otm40867
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR46059
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1922
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.880