DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SiaT and st8sia3

DIOPT Version :9

Sequence 1:	NP_523853.1	Gene:	SiaT / 37950	FlyBaseID:	FBgn0035050	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_001106903.1	Gene:	st8sia3 / 553510	ZFINID:	ZDB-GENE-060228-4	Length:	374	Species:	Danio rerio

Alignment Length:	407	Identity:	96/407 - (23%)
Similarity:	142/407 - (34%)	Gaps:	118/407 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 PRS-VFHVRWNPN--EKFIVESRENPAINSSKLAPHPRLKVSKNTKLTLSPKLYLCHD--KHSEL 147
            ||. :||..:...  .||:     :||..|...|.:..|:.|.|.:...|....|..:  :|.::
Zfish    45 PRMYMFHAGFRSQLAMKFL-----DPAFTSLNTALNENLQESSNWRFNRSAYAELSKEIAQHIDV 104

  Fly   148 CHNKTQQFRQRIVRAFEKAMVESVNESQANHYNVDYKPVFGDSFEEQYYPSTCLVMEAGVRVLRR 212
            .||.|             ....||...|..||:               |.|...|...|.. ||
Zfish   105 PHNFT-------------LTKNSVRVGQLMHYD---------------YSSHKYVFSIGEN-LR- 139

  Fly   213 KDAPFNKLPFGRLFPRQKLFRNVKDIKTCAIVSSAGSLAGSKLGRFIDTHDIVMRFNHAPTQGHE 277
                       .|.|......| |...|||:|.::|.|.||:.|..||.:|.|.|.|.|||:...
Zfish   140 -----------SLLPDASPVLN-KRYNTCAVVGNSGILTGSRCGPEIDKYDFVFRCNFAPTEVFR 192

  Fly   278 VDVGSKTTIRVVNSQVVTKPEFDFTRAPIFRNVTIAAWDPGKYNGTLED------WL------TS 330
            .|||.:|.:...|..::.|          :.|..:...|...:..:|:.      |:      ||
Zfish   193 RDVGRRTNLTTFNPSILEK----------YYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTS 247

  Fly   331 AD-----YDLFSNYELYRRRYPKSRAFLIDPHSVW----RLWQSLQMFAGNRPISKNPPSSGFIG 386
            |.     .|.|..::      .:.:..|..|.::.    |.|::.|       :|....|:|.:.
Zfish   248 ATVTRTLVDFFVEHK------GQLKVQLAWPGNIMQYVNRYWKTKQ-------LSPKRLSTGILM 299

  Fly   387 LALLLPHCPQVDFVEY-----VPSTRLNGRCHYYSKEMNSACTFGSW---HPLAAE-KLMALDMN 442
            ..|....|.||....:     .|:|......|||.|:.....|  .|   |.|..| ||:   ..
Zfish   300 FTLASSLCEQVHLYGFWPFGWDPNTGKELPYHYYDKKGTKFTT--KWQESHQLPTEFKLL---FK 359

  Fly   443 MAEDDDMSVFQFGILRI 459
            |..|        |:|::
Zfish   360 MHAD--------GVLKL 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SiaT	NP_523853.1	Glyco_transf_29	224..437	CDD:279159	61/242 (25%)
st8sia3	NP_001106903.1	Glyco_transf_29	107..368	CDD:279159	79/338 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2692
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810