Protein Alignment SiaT and ST8SIA6

DIOPT Version :9

• Sequence 1: NP_523853.1
• Gene: SiaT / 37950
• FlyBaseID: FBgn0035050
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001004470.1
• Gene: ST8SIA6 / 338596
• HGNCID: 23317
• Length: 398
• Species: Homo sapiens
• Alignment Length: 431
• Identity: 89/431 - (20%)
• Similarity: 143/431 - (33%)
• Gaps: 129/431 - (29%)

  Fly    96 WNPNEK------FIVESRE----NPAINSSKLAPHPRLKVSKNTKLTLSPKLYLCHDKHSELCHN 150
            |.|.:.      .:.||||    .||...:..:|...:..:.|:.......|.|     :|.|
Human    24 WCPADAPGRARILVEESREATHGTPAALRTLRSPATAVPRATNSTYLNEKSLQL-----TEKC-- 81

  Fly   151 KTQQFRQRIVRAFEKAMVESVNESQANHYNVDYKPVFGD-------SFEEQY------YPSTCLV 202
            |..|:.           :||.:.....:...||..:..|       ...|:|      ..|.|..
Human    82 KNLQYG-----------IESFSNKTKGYSENDYLQIITDIQSCPWKRQAEEYANFRAKLASCCDA 135

  Fly   203 MEAGV--------------RVLRRKDAPFNKLPFGRLFPRQKLFRNVKDIKTCAIVSSAGSLAGS 253
            ::..|              .|..:|:.|..|..| .:||..:.|.:. ....||:|.:.|.|..|
Human   136 VQNFVVSQNNTPVGTNMSYEVESKKEIPIKKNIF-HMFPVSQPFVDY-PYNQCAVVGNGGILNKS 198

  Fly   254 KLGRFIDTHDIVMRFNHAPTQGH-EVDVGSKTTIRVVNSQVVTKPEFDFTRAPIFRNVTIAAWDP 317
            ..|..||..|.|.|.|..||.|. ..||||||.:..:|..::|.
Human   199 LCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITL--------------------- 242

  Fly   318 GKYNGT-------LEDWLTSAD-YDLFSNYEL-----------YRRRYPKSRAFLIDPHSVWRLW 363
             ||...       |||..|..| :.|...:..           |.....|:|..::..|.  :..
Human   243 -KYGNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVLFFHP--KYL 304

  Fly   364 QSLQMFAGNRPISKNPPSSGFIGLALLLPHCPQVDF---------VEYVPSTRLNGRCHYYSKEM 419
            :.|.:|...:.::....|:|.:..::.:..|..|..         ||.:|.:.     |||..::
Human   305 KDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIPVSH-----HYYDNKL 364

  Fly   420 NSACTFGSWHPLAAEKLMALDMNMAEDDDMSVFQFGILRIR 460
            ..    ..:|.:..|....|.::|.          |||:::
Human   365 PK----HGFHQMPKEYSQILQLHMK----------GILKLQ 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SiaT	NP_523853.1	Glyco_transf_29	224..437	CDD:279159	53/241 (22%)
ST8SIA6	NP_001004470.1	Glyco_transf_29	138..391	CDD:395627	64/297 (22%)
		Substrate binding. /evidence=ECO:0000250|UniProtKB:O43173	236..238		1/1 (100%)
		Substrate binding. /evidence=ECO:0000250|UniProtKB:O43173	322..324		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2692
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810