Protein Alignment SiaT and ST8SIA5

DIOPT Version :10

• Sequence 1: NP_523853.1
• Gene: SiaT / 37950
• FlyBaseID: FBgn0035050
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001294915.1
• Gene: ST8SIA5 / 29906
• HGNCID: 17827
• Length: 412
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 78/363 - (21%)
• Similarity: 135/363 - (37%)
• Gaps: 101/363 - (27%)

  Fly   149 HNKTQ--QFRQRIVRAFEKAMVE----------------SVNESQANHYNVDYK-----PVFGDS 190
            :|.|:  :.|..|:.....:||:                ::|.|:||.:.....     |.|..:
Human    91 YNSTRCLELRHEILEVKVLSMVKQSELFDRWKSLQMCKWAMNISEANQFKSTLSRCCNAPAFLFT 155

  Fly   191 FEE--------QYYPSTCLVMEAGVRVLRR--KDAPFNKLPFGRLFPRQKLFRNVKDIKTCAIVS 245
            .::        :|...|..:......:.|.  ||.|:.:..|                |.||:|.
Human   156 TQKNTPLGTKLKYEVDTSGIYHINQEIFRMFPKDMPYYRSQF----------------KKCAVVG 204

  Fly   246 SAGSLAGSKLGRFIDTHDIVMRFNHAP-TQGHEVDVGSKTTIRVVNSQVVTK--PEFDFTRAPIF 307
            :.|.|..|:.||.|::.|.|.|.|..| ::.:.:|||.||.:..||..::|:  .:.:..|.|.:
Human   205 NGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITERFHKLEKWRRPFY 269

  Fly   308 R------NVTIAAWDPGKYNGTLEDWLTSADYDLFSNYELYRRRYPKSRAFLIDPHSVWRLWQSL 366
            |      |.::..  |..||....|......| :..::|..:..|.....:|:   :|.|.|.||
Human   270 RVLQVYENASVLL--PAFYNTRNTDVSIRVKY-VLDDFESPQAVYYFHPQYLV---NVSRYWLSL 328

  Fly   367 QMFAGNRPISKNPPSSGFIGLALLLPHCPQVDFVEY----VPSTRLNGRCHYYSKEMNSACTFGS 427
            .:.|       ...|:|.|.:...|..|.:|....:    :..:.|....|||    ::......
Human   329 GVRA-------KRISTGLILVTAALELCEEVHLFGFWAFPMNPSGLYITHHYY----DNVKPRPG 382

  Fly   428 WHPLAAEKLMALDMNMAEDDDMSVFQF------GILRI 459
            :|.:.:|                :|.|      ||||:
Human   383 FHAMPSE----------------IFNFLHLHSRGILRV 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SiaT	NP_523853.1	GT29_ST6GAL1_2	199..469	CDD:467696	65/282 (23%)
ST8SIA5	NP_001294915.1	GT29_ST8SIA5	134..406	CDD:467718	71/320 (22%)