DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SiaT and St6galnac1

DIOPT Version :9

Sequence 1:	NP_523853.1	Gene:	SiaT / 37950	FlyBaseID:	FBgn0035050	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_001099329.1	Gene:	St6galnac1 / 287920	RGDID:	1562048	Length:	520	Species:	Rattus norvegicus

Alignment Length:	563	Identity:	114/563 - (20%)
Similarity:	190/563 - (33%)	Gaps:	204/563 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SSGQSQALLSCLIIAVCAALIIQ---------------SGHIQGVKAQPGREPGEVNSRQPGNGA 57
            |.||:..||:.|::......:::               ...:|||..:|..: |.:.:..|   .
  Rat     9 SQGQTFLLLTGLMLLFILPSVVKEPSTRVSRYQFIEDNESSLQGVPQKPAPQ-GPIVTLTP---T 69

  Fly    58 YENSTGTERRLRKVIWKCI-----PTGNGTTGHRVPRSVFHVRWNPNEKFIVESRENPAINSSKL 117
            ..|...|..|.:   |..:     .|..|..|..|.:.:..:|..|         |||     |.
  Rat    70 VHNKKTTSVRTK---WVELQKQDRATARGERGEGVEKKLQAIRLAP---------ENP-----KG 117

  Fly   118 APHPRLKVSKNTKLTLSPKLYLCHDKHSELCHNKTQQ------FRQRIVR------AFEKAMVES 170
            ...|.:|...:..|...|:      ....|...|||.      .::::|:      :|.....:.
  Rat   118 KAEPEVKTPASKHLDKLPR------ATGALSTRKTQMATGAAPAKKKVVQPTPTPASFPHLTTQR 176

  Fly   171 VNESQANHYNVDYKPVFGDSFEEQY-----------------------------YPSTCLVMEAG 206
            ....:|:    |:|......|||:|                             .|:..|.:::|
  Rat   177 RQRLKAS----DFKSEPRWDFEEEYSLDGGSLQTTCPGSVKITASHSPWLQNIFLPNITLFLDSG 237

  Fly   207 VRVLRRKDAPFNKL-----PFGRL----------------FPRQKLF------RNVKDIKTCAIV 244
                |...:.:.:|     |||.:                .|:|:|.      ||:..| |||:|
  Rat   238 ----RFNQSEWYRLEHFTPPFGFMELNQSLVQKVVSRFPPVPQQQLLLASLPTRNLTCI-TCAVV 297

  Fly   245 SSAGSLAGSKLGRFIDTHDIVMRFNHAPTQGHEVDVGSKTT------IRVVNSQVVTKPEFDFTR 303
            .:.|.|..|::|:.||:||.|.|.:.|..:|:|.|||::|:      ..:|.| ::......|..
  Rat   298 GNGGILNNSRMGQEIDSHDYVFRLSGAVIKGYEQDVGTRTSFYGFTAFSLVQS-ILNLGRQGFQH 361

  Fly   304 APIFRNVTIAAWDPGKYNGTLE-----DWL-------TSADYDLF----SNYELYRRRYPKSRAF 352
            .|:.::|        :|...||     :||       |.|:..|:    ...|.:|......|.|
  Rat   362 VPLGKDV--------RYLHFLEGTRDYEWLEAMFLNRTMANTKLYWFRHRPQEAFREALDLDRYF 418

  Fly   353 LIDPHSV-----------------WRLWQSLQMFAGNRPISKNPPSSGFIGLALLLPHCPQVDFV 400
            |:.|..:                 |||::               |::|.:.|...|..|.:|...
  Rat   419 LVHPDFLRYMKNRFLRSKTLDTAHWRLYR---------------PTTGALLLLTALHLCDKVSAY 468

  Fly   401 EYVPSTRLNGRCHYYSKEMNSACTFGSW--------HPLAAEK 435
            .::.........|||..         ||        |..|.|:
  Rat   469 GFITQGHERFSDHYYDT---------SWKRLIFYINHDFALER 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SiaT	NP_523853.1	Glyco_transf_29	224..437	CDD:279159	63/281 (22%)
St6galnac1	NP_001099329.1	Glyco_transf_29	232..518	CDD:279159	70/309 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2692
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810