DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SiaT and ST6GALNAC4

DIOPT Version :9

Sequence 1:	NP_523853.1	Gene:	SiaT / 37950	FlyBaseID:	FBgn0035050	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	XP_011516829.1	Gene:	ST6GALNAC4 / 27090	HGNCID:	17846	Length:	325	Species:	Homo sapiens

Alignment Length:	248	Identity:	60/248 - (24%)
Similarity:	95/248 - (38%)	Gaps:	56/248 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 FNKLPFGRLFPRQKLFRNVKDIKTCAIVSSAGSLAGSKLGRFIDTHDIVMRFNHAPTQGHEVDVG 281
            ::.:|.|:...|:       ..::||:|||:|.:.||.||..||:.:.|.|.|.|||.|.|.|||
Human    82 YSSVPDGKPLVRE-------PCRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVG 139

  Fly   282 SKTTIRVVNSQVVTKPEFDFTRAPIF-----------RNVTIAAWDPGKYNGTLEDWLTSADYDL 335
            .::|:|||:          .|..|:.           |:.....|..|::            .|.
Human   140 QRSTLRVVS----------HTSVPLLLRNYSHYFQKARDTLYMVWGQGRH------------MDR 182

  Fly   336 FSNYELYR------RRYPKSRAFLIDPHSVWRLWQSLQMFAG-NRPISKNPPSSGFIGLALLLPH 393
            ......||      |.||..:.:......:....|..|...| ||..|.:..|:|:..:.|.|..
Human   183 VLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILALEL 247

  Fly   394 CPQVDFVEYVPSTRLNGRC------HYYSKEMNSACTFGSWH---PLAAEKLM 437
            |.::.....|..:....:.      ||:.|.....|.....|   |.:|.:.:
Human   248 CEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYLAHEQAPRSAHRFI 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SiaT	NP_523853.1	Glyco_transf_29	224..437	CDD:279159	58/239 (24%)
ST6GALNAC4	XP_011516829.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2692
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810