DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SiaT and St8sia3

DIOPT Version :9

Sequence 1:	NP_523853.1	Gene:	SiaT / 37950	FlyBaseID:	FBgn0035050	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_037161.2	Gene:	St8sia3 / 25547	RGDID:	3680	Length:	380	Species:	Rattus norvegicus

Alignment Length:	367	Identity:	80/367 - (21%)
Similarity:	123/367 - (33%)	Gaps:	122/367 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 SPKLYLCH----------------------------DKHSELCHNKTQQFRQR--------IVRA 162
            :|::|:.|                            :|.|:...|:|....||        :::.
  Rat    49 APRMYMFHAGFRSQFALKFLDPSFVPITNSLTHELQEKPSKWTFNRTAFLHQRQEILQHVDVIKN 113

  Fly   163 FEKAMVESVNESQANHYNV-DYKPVFGDSFEEQYYPSTCLVMEAGVRVLRRKDAPFNKLPFGRLF 226
            |.... .||...|..||:. .:|.||..|..                             |..|.
  Rat   114 FSLTK-NSVRIGQLIHYDYSSHKYVFSISNN-----------------------------FRSLL 148

  Fly   227 PRQKLFRNVKDIKTCAIVSSAGSLAGSKLGRFIDTHDIVMRFNHAPTQGHEVDVGSKTTIRVVNS 291
            |......| |....||:|.::|.|.||:.|:.||..|.|.|.|.|||:....|||.||.:...|.
  Rat   149 PDVSPILN-KRYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFHKDVGKKTNLTTFNP 212

  Fly   292 QVVTKPEFDFTRAPIFRNVTIAAWDPGKYNGTLED------WL------TSAD-----YDLFSNY 339
            .::.|          :.|..:...|...:..:|:.      |:      |||.     .|.|..:
  Rat   213 SILEK----------YYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEH 267

  Fly   340 ELYRRRYPKSRAFLIDPHSVW----RLWQSLQMFAGNRPISKNPPSSGFIGLALLLPHCPQVDF- 399
            .      .:.:..|..|.::.    |.|:       |:.:|....|:|.:...|....|.::..
  Rat   268 R------GQLKVQLAWPGNIMQHVNRYWK-------NKHLSPKRLSTGILMYTLASAICEEIHLY 319

  Fly   400 ----VEYVPSTRLNGRCHYYSKEMNSACTFGSW---HPLAAE 434
                ..:.|:||.:...|||.|:.....|  .|   |.|.||
  Rat   320 GFWPFGFDPNTREDLPYHYYDKKGTKFTT--KWQESHQLPAE 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SiaT	NP_523853.1	Glyco_transf_29	224..437	CDD:279159	60/240 (25%)
St8sia3	NP_037161.2	Glyco_transf_29	113..376	CDD:395627	71/303 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2692
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810