Protein Alignment KHK and Adk1

DIOPT Version :10

• Sequence 1: XP_006712071.1
• Gene: KHK / 3795
• HGNCID: 6315
• Length: 371
• Species: Homo sapiens
• Sequence 2: NP_731676.2
• Gene: Adk1 / 41476
• FlyBaseID: FBgn0037995
• Length: 396
• Species: Drosophila melanogaster
• Alignment Length: 276
• Identity: 56/276 - (20%)
• Similarity: 91/276 - (32%)
• Gaps: 88/276 - (31%)

Human    37 WQRGGNASNSCTVLS-LLGAP--CAFMGSMAPGHVADSFVLDDLRRYSVDLRYTVFQTTGSVPIA 98
            :..||...||..:.. ::..|  ..|:||:....:.|...    :|...|...|::|....:|..
  Fly   109 YSAGGACQNSMRIFQWIVQTPFRAVFIGSVGKDKLGDRIE----KRAKSDGLLTLYQLKEELPTG 169

Human    99 T--VIINEASGS------RTILYYDSFLVADFRRRGVD------------------VSQVAWQSK 137
            :  ||||..:.|      ...|:.|.::..|.....:|                  |.:||
  Fly   170 SCAVIINGPNRSLVANLGAASLFSDDWIDEDDNICALDRAEYFYFTGFFLAVCPPAVERVA---- 230

Human   138 GDTPSSCCIINNSNGNRTIVLHDTS--------------LPDVSATDFEKVDLTQFK----WIHI 184
                ..||     ..||.::|:.::              |..|......|.:...|.    |
  Fly   231 ----RMCC-----ETNRIMILNFSAVFVLQMQKEALGNILQYVDIIICNKEEAIAFSDTNDW--- 283

Human   185 EGRNASEQVKMLQRIDAHNTR----------------QPPEQKIRVSVEVEKPREELFQLFGYGD 233
            :.:|..|....||::...|||                |..::.:...|...| :.|:|...|.||
  Fly   284 KTKNIFEIGSRLQQMPKENTRPRLVMITDAVCPVLVFQDNDRVLEYPVPPVK-QGEIFDTNGCGD 347

Human   234 V-VG---APFSLSLPL 245
            . ||   |.:...:||
  Fly   348 AFVGGFLAMYVQRMPL 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KHK	XP_006712071.1	ribokinase_pfkB_like	5..>235	CDD:469648	51/261 (20%)
Adk1	NP_731676.2	adenosine_kinase	54..382	CDD:238573	56/276 (20%)