Protein Alignment KHK and CG7328

DIOPT Version :10

• Sequence 1: XP_006712071.1
• Gene: KHK / 3795
• HGNCID: 6315
• Length: 371
• Species: Homo sapiens
• Sequence 2: NP_649181.1
• Gene: CG7328 / 40204
• FlyBaseID: FBgn0036942
• Length: 306
• Species: Drosophila melanogaster
• Alignment Length: 274
• Identity: 82/274 - (29%)
• Similarity: 121/274 - (44%)
• Gaps: 69/274 - (25%)

Human     4 KQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHV 68
            |.:||||..|:|.:::...||.||::.|||...|||||||||..|||.:||....|.|.::.
  Fly     5 KSVLCVGCTVIDFVTINGSYPMEDTDRRCLDGFWQRGGNASNVSTVLRVLGCKVDFFGMLSR--- 66

Human    69 ADSF--VLDDLRRYSVDLRYTVFQTTGSVPIATVIINEASGSRTILYYDSFLVADFRRRGVDVSQ 131
            :|.|  :||||.:..:......| |....|.::||:.:.||:|||::
  Fly    67 SDGFRVLLDDLSKREIGTNDCPF-TDRDPPFSSVILAQDSGTRTIIH------------------ 112

Human   132 VAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKML 196
                         |              :...|..:..||.|::|:|:.|:|.|.||....:||:
  Fly   113 -------------C--------------NKDYPQTTYEDFSKINLSQYGWVHFEARNTPHTLKMM 150

Human   197 QRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVGAPFS------LSLPLP-------AN 248
            |.|..:|.|  ..|.|.:|::.|...|:..:|....|.|  .||      |....|       |:
  Fly   151 QSIREYNQR--TGQGIIISLDFETRYEQNQELCAPCDFV--VFSKELAGQLGWKTPRQSCEELAS 211

Human   249 LVLKGSQNP-FILP 261
            .:.:|...| ||.|
  Fly   212 KIPEGGPKPVFICP 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KHK	XP_006712071.1	ribokinase_pfkB_like	5..>235	CDD:469648	70/231 (30%)
CG7328	NP_649181.1	Ketohexokinase	6..297	CDD:238914	81/273 (30%)