DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mmp1 and MMP

DIOPT Version :9

Sequence 1:	NP_726473.2	Gene:	Mmp1 / 37949	FlyBaseID:	FBgn0035049	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	NP_177174.1	Gene:	MMP / 843353	AraportID:	AT1G70170	Length:	378	Species:	Arabidopsis thaliana

Alignment Length:	282	Identity:	101/282 - (35%)
Similarity:	128/282 - (45%)	Gaps:	38/282 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 YLSQFGYLPASARNPASSGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDRV- 99
            |..:|||:|.:.....:....|  ...:|:|.:|:...||:||||||.|::.:.:||||..|.|
plant    65 YFQRFGYIPETFSGNFTDDFDD--ILKAAVELYQTNFNLNVTGELDALTIQHIVIPRCGNPDVVN 127

  Fly   100 GT----GDSRS--------------KRYAL-QGS-RW--RVKNLTYKISKYPKRLKRVDVDAEIG 142
            ||    |..|.              |||.| .|. ||  ..::|||...  ||.....:|.:...
plant   128 GTSLMHGGRRKTFEVNFSRTHLHAVKRYTLFPGEPRWPRNRRDLTYAFD--PKNPLTEEVKSVFS 190

  Fly   143 RAFAVWSEDTDLTFTRKTS-GPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFPVFGGDAHFDDAE 206
            |||..||:.|.|.||...| ....|.|.|...:||||:.|||..|||||||.|. .|..|.|..|
plant   191 RAFGRWSDVTALNFTLSESFSTSDITIGFYTGDHGDGEPFDGVLGTLAHAFSPP-SGKFHLDADE 254

  Fly   207 LWTIGS--------PRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEPVFKLDEDDKAAI 263
            .|.:..        ....:|..||.||.||.|||.||....::|.|.....:....|..||...|
plant   255 NWVVSGDLDSFLSVTAAVDLESVAVHEIGHLLGLGHSSVEESIMYPTITTGKRKVDLTNDDVEGI 319

  Fly   264 QSLYGRKTNQLRPTNVYPATTQ 285
            |.|||...| ...|...|:||:
plant   320 QYLYGANPN-FNGTTSPPSTTK 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:279773	18/51 (35%)
		Peptidase_M10	115..268	CDD:278824	61/163 (37%)
		ZnMc_MMP	115..268	CDD:239805	61/163 (37%)
		HX	298..493	CDD:238046
MMP	NP_177174.1	PG_binding_1	62..115	CDD:396175	18/51 (35%)
MMP	NP_177174.1	Peptidase_M10	163..324	CDD:395334	61/163 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	97	1.000	Domainoid score	I2423
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	1	1.000	-	-		FOG0000127
OrthoInspector	1	1.000	-	-		mtm995
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10201
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.880