DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mmp1 and AT1G59970

DIOPT Version :9

Sequence 1:	NP_726473.2	Gene:	Mmp1 / 37949	FlyBaseID:	FBgn0035049	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	NP_176205.1	Gene:	AT1G59970 / 842291	AraportID:	AT1G59970	Length:	360	Species:	Arabidopsis thaliana

Alignment Length:	260	Identity:	93/260 - (35%)
Similarity:	123/260 - (47%)	Gaps:	30/260 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 YLSQFGYLPASARNPASSGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDRV- 99
            |..:|||:..:..  .:....|  ...|||..:|....|.:||:||:.|::.:..||||..|.:
plant    66 YFRRFGYITTTGN--CTDDFDD--VLQSAINTYQKNFNLKVTGKLDSSTLRQIVKPRCGNPDLID 126

  Fly   100 GTGDSR-------SKRYA-LQGS-RW--RVKNLTYKISKYPKRLKRVDVDAEIGRAFAVWSEDTD 153
            |..:..       :::|: ..|. ||  |.::|||..:  |:.....:|.....|||..|:|.|.
plant   127 GVSEMNGGKILRTTEKYSFFPGKPRWPKRKRDLTYAFA--PQNNLTDEVKRVFSRAFTRWAEVTP 189

  Fly   154 LTFTRKTS-GPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFPVFGGDAHFDDAELWTIGS----- 212
            |.|||..| ....|.|.|...|||||:.|||..||||||..|. .|..|.|..|.|.|.:
plant   190 LNFTRSESILRADIVIGFFSGEHGDGEPFDGAMGTLAHASSPP-TGMLHLDGDEDWLISNGEISR 253

  Fly   213 ---PRGT--NLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEPVFKLDEDDKAAIQSLYGRKTN 272
               |..|  :|..||.||.||.|||.||....|:|.|...|.:...:|.:||...||.|||...|
plant   254 RILPVTTVVDLESVAVHEIGHLLGLGHSSVEDAIMFPAISGGDRKVELAKDDIEGIQHLYGGNPN 318

Fly 273 272
plant 319 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:279773	15/51 (29%)
		Peptidase_M10	115..268	CDD:278824	67/165 (41%)
		ZnMc_MMP	115..268	CDD:239805	67/165 (41%)
		HX	298..493	CDD:238046
AT1G59970	NP_176205.1	PG_binding_1	63..114	CDD:366659	15/51 (29%)
AT1G59970	NP_176205.1	Peptidase_M10	151..313	CDD:334067	66/164 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	97	1.000	Domainoid score	I2423
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	1	1.000	-	-		FOG0000127
OrthoInspector	1	1.000	-	-		mtm995
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10201
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.880