Protein Alignment Mmp1 and Mmp9

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_112317.2
• Gene: Mmp9 / 81687
• RGDID: 621320
• Length: 708
• Species: Rattus norvegicus
• Alignment Length: 712
• Identity: 178/712 - (25%)
• Similarity: 248/712 - (34%)
• Gaps: 269/712 - (37%)

  Fly     1 MTNCQSSVFIVVGTLFSIMAAAQSAP-------------VSTTTQAEIYLSQFGYLPASARNPAS 52
            |...|..:.:::...:|..|..|..|             ::.|..||.||.::||      ..|:
  Rat     1 MNPWQPLLLVLLALGYSFAAPHQRQPTYVVFPRDLKTSNLTDTQLAEDYLYRYGY------TRAA 59

  Fly    53 SGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDRVGTGDSRSKRYALQGS-RW 116
            ..:.::::...|:...|....|..|||||:||:|.:..|||||.| ||      |....:|. :|
  Rat    60 QMMGEKQSLRPALLMLQKQLSLPQTGELDSETLKAIRSPRCGVPD-VG------KFQTFEGDLKW 117

  Fly   117 RVKNLTYKISKYPKRLKRVDVDAEIGRAFAVWSEDTDLTFTRKTSGPVHIEIKFVESEHGDGDAF 181
            ...|:||.|..|.:.|.|..:|....|||||||..|.|||||.......|.|:|..:|||||..|
  Rat   118 HHHNITYWIQSYTEDLPRDVIDDSFARAFAVWSAVTPLTFTRVYGLEADIVIQFGVAEHGDGYPF 182

  Fly   182 DGQGGTLAHAFFPVFG--GDAHFDDAELWTIGS-------------------------------- 212
            ||:.|.|||||.|..|  |||||||.|||::|.
  Rat   183 DGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGAVVPTYFGNANGAPCHFPFTFEGRSYLSCTT 247

  Fly   213 ----------------------------------------------------------------- 212
                                                                             
  Rat   248 DGRNDGKPWCGTTADYDTDRKYGFCPSENLYTEHGNGDGKPCVFPFIFEGHSYSACTTKGRSDGY 312

  Fly   213 ----------------------------------------------------------------- 212
                                                                             
  Rat   313 RWCATTANYDQDKLYGFCPTRADVTVTGGNSAGEMCVFPFVFLGKQYSTCTGEGRSDGRLWCATT 377

  Fly   213 -------------PRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEPVFKLDEDDKAAIQ 264
                         .:|.:||.||||||||:|||.||....|||.|.|...|. ..|.|||...||
  Rat   378 SNFDADKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYHYHED-SPLHEDDIKGIQ 441

  Fly   265 SLYGRKTNQLRPTNVYPATT---QRPYSPP----------------------------------- 291
            .||||.:   :|....||||   .:|.:||
  Rat   442 HLYGRGS---KPDPRPPATTAAEPQPTAPPTMCPTAPPMAYPTGGPTVAPTGAPSPGPTGPPTAG 503

  Fly   292 --KVPLDDSICKDS--KVDTLFNS---AQGETYAFKGDKYYKLTT--DSVEEGYPQLISKGWPGL 347
              :.|.:.|...|:  .|| :|::   .||..:.||..:|:|.:.  .|..:| |.||::.||.|
  Rat   504 PSEAPTESSTPVDNPCNVD-VFDAIADIQGALHFFKDGRYWKFSNHGGSQLQG-PFLIARTWPAL 566

  Fly   348 PGNIDAAF-TYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIPDHLDAAMVWGGNGKIYF 411
            |..:::|| ..::.|.:||.|.:.|.|.|:.:.|  |:.:.:...|....|...::....||...
  Rat   567 PAKLNSAFEDPQSKKIFFFSGRKMWVYTGQSVLG--PRSLDKLGLGSEVTLVTGLLPRRGGKALL 629

  Fly   412 FKGSKFWRFDPAKRPPVKASYPKPISNWEGVPNNLDAALKYTNGYTYFFKGDKYYRFHDARF 473
            ....:.|:||...:.....|..:..:.:.|||         .|.:..|...||.|..||..|
  Rat   630 ISRERIWKFDLKSQKVDPQSVTRLDNEFSGVP---------WNSHNVFHYQDKAYFCHDKYF 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223	18/55 (33%)
		Peptidase_M10	115..268	CDD:425668	81/329 (25%)
		HX	298..493	CDD:238046	50/184 (27%)
Mmp9	NP_112317.2	PG_binding_1	42..95	CDD:460223	19/58 (33%)
		Peptidase_M10	116..445	CDD:425668	81/329 (25%)
		FN2	224..272	CDD:128373	0/47 (0%)
		FN2	282..330	CDD:128373	0/47 (0%)
		FN2	341..389	CDD:128373	0/47 (0%)
		PT	458..489	CDD:282710	4/30 (13%)
		PT	475..510	CDD:282710	1/34 (3%)
		HX	517..707	CDD:238046	48/179 (27%)