Protein Alignment Mmp1 and mmp15

DIOPT Version :9

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001015921.1
• Gene: mmp15 / 548675
• XenbaseID: XB-GENE-1014388
• Length: 648
• Species: Xenopus tropicalis
• Alignment Length: 626
• Identity: 217/626 - (34%)
• Similarity: 317/626 - (50%)
• Gaps: 74/626 - (11%)

  Fly    10 IVVGTLFSIMAAAQSAPVST-TTQAEIYLSQFGYLPASARNPASSGLHDQRTWVSAIEEFQSFAG 73
            :::|..|.::.....|..|. .::||.:|..:||||.::|.  .|.:...:...|||.|.|.|.|
 Frog    21 LLLGWTFLLICCQGYAATSDWDSKAEAWLKLYGYLPQTSRQ--MSTMRSLQILSSAISEMQRFYG 83

  Fly    74 LNITGELDAETMKLMSLPRCGVRDRVGT---GDSRSKRYALQGSRWRVKNLTYKISKYPKRL-KR 134
            :..|||||..|.:.|..|||||.|:.||   .:.|.||||..|.:|..::|||.|..|..:| ..
 Frog    84 IPETGELDHTTTEWMQKPRCGVPDQFGTRVKSNMRRKRYAHTGRKWNQQHLTYSIQNYSDKLGMH 148

  Fly   135 VDVDAEIGRAFAVWSEDTDLTF-------TRKTSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAF 192
            ..:|| |.:||.|||:.|.|||       .|:......|.|.|....|||...|||.||.||||:
 Frog   149 NSIDA-IRKAFDVWSKATSLTFREVPYEAVRQRHSSADILILFASGFHGDSSPFDGPGGFLAHAY 212

  Fly   193 F--PVFGGDAHFDDAELWTIGSP--RGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEPV- 252
            |  |..|||||||..|.||:.:.  .|.:||.||.||.||||||.||:..||:|||||:..:..
 Frog   213 FPGPGMGGDAHFDSEEPWTVENMDLAGNHLFLVAVHELGHSLGLEHSNNPSAIMAPFYQWMDTED 277

  Fly   253 FKLDEDDKAAIQSLYGRKTNQLRPTNVYPATT--------------------QRPYS--PPKVPL 295
            |:|.|||:..||.|||...:|: |:...|..|                    :||.:  ||:.|.
 Frog   278 FQLPEDDRRGIQQLYGPPVDQI-PSTQSPLPTPGKPEVPDKRPPKPPPRGKPERPGNAPPPRSPS 341

  Fly   296 D-----DSICKDSKVDTLFNSAQGETYAFKGDKYYKLTTDSVEEGYPQLISKGWPGLPGNIDAAF 355
            :     .:|| :...|.: :..:||.:.|||..::::..:.|.:.||..|...|.|||.||.||:
 Frog   342 NPDQYGPNIC-EGNFDAV-SVLRGEMFVFKGAWFWRVRHNRVLDNYPMPIGHFWRGLPPNITAAY 404

  Fly   356 TYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIP-DHLDAAMVWGGNGKIYFFKGSKFWR 419
            ...:||..||||.:||.::...::..||:.::....||| |.:|.|:.|...|..|.|:|.|:||
 Frog   405 ERHDGKFVFFKGEKYWLFREANLEAGYPQPLTSFGYGIPYDRIDTAIFWEPTGHTYLFRGDKYWR 469

  Fly   420 FDPAKRPPVKASYPKPISNWEGVPNNLDAA-LKYTNGYTYFFKGDKYYRFHDARFAVDSATPPFP 483
            |:...| .....|||||:.|.|:|:....| |...:.||||:||.||::|.:.:...:   |.:|
 Frog   470 FNEESR-SADVGYPKPITVWAGIPDTPKGAFLSSDSTYTYFYKGAKYWKFDNQQLKTE---PGYP 530

  Fly   484 RPTAHWWFGCKNTPSSTGNIV-EGSDNEFEQHSMIPHADDGNGDDFDAAVGDHQSN---DEPIVP 544
            :.....:.||:.......::| ...|.|....:....::|.:..|.|:| |....|   |..:|.
 Frog   531 KSILRDFMGCQEEVFQDPDVVPRWPDVEHPPFNPDVESEDKDDKDSDSA-GREDPNTGRDVDVVV 594

  Fly   545 EVAERTGNGAMSQSKLTSSSAVSTVIT--TILMCLVSKLIV 583
            .:.|           .|.:.:|:.||.  .:|:|::..:.|
 Frog   595 HIDE-----------YTRAVSVAMVIVPLLLLLCILGLIYV 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:279773	22/55 (40%)
		Peptidase_M10	115..268	CDD:278824	77/165 (47%)
		ZnMc_MMP	115..268	CDD:239805	77/165 (47%)
		HX	298..493	CDD:238046	67/196 (34%)
mmp15	NP_001015921.1	PG_binding_1	45..98	CDD:366659	22/54 (41%)
		Peptidase_M10	128..293	CDD:334067	77/165 (47%)
		HX	348..540	CDD:238046	67/197 (34%)
		DUF3377	579..648	CDD:371766	13/58 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	43	1.000	Domainoid score	I12189
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	326	1.000	Inparanoid score	I2436
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47536
Panther	1	1.100	-	-	O	PTHR10201
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3504
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.100