| Sequence 1: | NP_726473.2 | Gene: | Mmp1 / 37949 | FlyBaseID: | FBgn0035049 | Length: | 584 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004521.1 | Gene: | MMP2 / 4313 | HGNCID: | 7166 | Length: | 660 | Species: | Homo sapiens |
| Alignment Length: | 681 | Identity: | 179/681 - (26%) |
|---|---|---|---|
| Similarity: | 243/681 - (35%) | Gaps: | 237/681 - (34%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 11 VVGTLFSIMAAAQS---------APVSTTTQAEIYLSQFGYLPASARNPASSGLHDQRTWV--SA 64
Fly 65 IEEFQSFAGLNITGELDAETMKLMSLPRCGVRDRVGTGDSRSKRYALQGSRWRVKNLTYKISKYP 129
Fly 130 KRLKRVDVDAEIGRAFAVWSEDTDLTFTRKTSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFP 194
Fly 195 --VFGGDAHFDDAELWTIGS--------------------------------------------- 212
Fly 213 ----------------------------------------------------------------- 212
Fly 213 ----------------------------------------------------------------P 213
Fly 214 RGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEPVFKLDEDDKAAIQSLYGRKTNQLRPTN 278
Fly 279 VYPATTQRPYSPPKVPLDDSICKDSKVDTLFNSAQGETYAFKGDKYYKLTTDSVEEGYPQLISKG 343
Fly 344 WPGLPGNIDAAF-TYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIP---DHLDAAMVWG 404
Fly 405 GNGKIYFFKGSKFWRFDPAKRPPVKASYPKPISN-WEGVPNNLDAALKYT-NGYTYFFKGDKYYR 467
Fly 468 FHD-----ARFAVDSATPPFPRPTAHWWFGC 493 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mmp1 | NP_726473.2 | PG_binding_1 | 32..88 | CDD:279773 | 16/57 (28%) |
| Peptidase_M10 | 115..268 | CDD:278824 | 77/328 (23%) | ||
| ZnMc_MMP | 115..268 | CDD:239805 | 77/328 (23%) | ||
| HX | 298..493 | CDD:238046 | 62/205 (30%) | ||
| MMP2 | NP_004521.1 | PG_binding_1 | <70..97 | CDD:307564 | 9/26 (35%) |
| Cysteine switch. /evidence=ECO:0000250 | 100..107 | 4/12 (33%) | |||
| Collagenase-like 1 | 110..221 | 49/110 (45%) | |||
| Peptidase_M10 | 118..446 | CDD:306839 | 77/328 (23%) | ||
| Collagen-binding | 222..396 | 1/173 (1%) | |||
| FN2 | 226..274 | CDD:128373 | 0/47 (0%) | ||
| FN2 | 284..332 | CDD:128373 | 0/47 (0%) | ||
| FN2 | 342..390 | CDD:128373 | 0/47 (0%) | ||
| Collagenase-like 2 | 397..465 | 33/70 (47%) | |||
| Required for inhibitor TIMP2 binding. /evidence=ECO:0000269|PubMed:1655733 | 414..660 | 83/268 (31%) | |||
| HX | 466..660 | CDD:238046 | 63/213 (30%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1565 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1075463at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR10201 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X44 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 5 | 4.920 | |||||