Protein Alignment Mmp1 and Mmp2

DIOPT Version :9

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Alignment Length: 778
• Identity: 200/778 - (25%)
• Similarity: 280/778 - (35%)
• Gaps: 275/778 - (35%)

  Fly    20 AAAQSAPVSTTTQAEI---YLSQFGYLPASARNPASSGLHDQRTWVSAIEEFQSFAGLNITGELD 81
            ||.:|....|....:|   ||.||.|||.|.....:....||..  .||...|||..:.:|||:|
  Fly    34 AATRSKKAKTAISEDIMYNYLMQFDYLPKSDLETGALRTEDQLK--EAIRSLQSFGNITVTGEID 96

  Fly    82 AETMKLMSLPRCGVRDR--------------VGTGDSRSKRYALQGSRWRVKNLTYKI--SKYPK 130
            :.|.:|:..|||||.||              :|: :.|.:|:||||.:|...:||:.:  ...|.
  Fly    97 SATARLIQKPRCGVGDRRSADSFSPDNLYHEIGS-NVRVRRFALQGPKWSRTDLTWSMVNRSMPD 160

  Fly   131 RLKRVDVDAEIGRAFAVWSEDTDLTFTRKTSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFP- 194
            ..|   |:..:..|..||:..:.|||....|....|:|.|....||||..|||.|..|||||:|
  Fly   161 ASK---VERMVQTALDVWANHSKLTFREVYSDQADIQILFARRAHGDGYKFDGPGQVLAHAFYPG 222

  Fly   195 -VFGGDAHFDDAELWTI----GSPRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEPVFK 254
             ..|||||||..|.|..    ....|||...||.||.||||||:||....|:|.|:|:..|....
  Fly   223 EGRGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGN 287

  Fly   255 LDEDDKAAIQSLYGRK-----------------TNQLR--------------------------- 275
            |.:||:..||.|||.|                 |..:|
  Fly   288 LPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNR 352

  Fly   276 ----------------------------------------------------------------- 275
                                                                             
  Fly   353 ARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKS 417

  Fly   276 ----------------------------------------------------------------P 276
                                                                            |
  Fly   418 QWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTP 482

  Fly   277 T-NVYPATTQRPY----------SPPKVPLDDSICKDSKVDTLFNS---AQGETYAFKGDKYYKL 327
            | |..|..|.:||          :.|:.|..|| |.     |.:::   .:||.:.|:|...:::
  Fly   483 TANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDS-CM-----TYYDAISIIRGELFIFRGPYLWRI 541

  Fly   328 TTDSVEEGYPQLISKGWPGLPGN---IDAAFTYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEG 389
            .|..:..|||..|.:.|..||.|   :||.:..|..:..||.|.:|:.:....:...:||.::.
  Fly   542 GTSGLYNGYPTEIRRHWSALPENLTKVDAVYENKQRQIVFFIGREYYVFNSVMLAPGFPKPLAS- 605

  Fly   390 FTGIP---DHLDAAMVWGGNGKIYFFKGSKFWRFDPAKRPPVKASYPKPISNWEGVPNNLDAALK 451
             .|:|   .|:||:.|||.|.:.|...|:.:||.|. ....|:..||:.:|.|.||..|:|||.:
  Fly   606 -LGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRIDD-YTGQVELDYPRDMSIWSGVGYNIDAAFQ 668

  Fly   452 YTNGYTYFFKGDKYYRFHDARFAVDSATPPFPRPTAHWWFGCKNTPSSTGNIVEGSDNEFEQHSM 516
            |.:|.|||||...|:.|:|.|..|..|.   .:.:|..|..|..           |.||
  Fly   669 YLDGKTYFFKNLGYWEFNDDRMKVAHAR---AKLSARRWMQCAR-----------SANE------ 713

  Fly   517 IPHADDGNGDDFDAAVGDHQSNDEPIVPEVAERTGNGAMSQSKLTSSSAVSTVITTILMCLVS 579
                           |.|.|.....:|.| .|.||.....:.:      ::..|.:||:..::
  Fly   714 ---------------VDDEQRWTASLVSE-GEETGRSGSRELR------INHFILSILLLAIA 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:279773	21/58 (36%)
		Peptidase_M10	115..268	CDD:278824	65/160 (41%)
		ZnMc_MMP	115..268	CDD:239805	65/160 (41%)
		HX	298..493	CDD:238046	65/203 (32%)
Mmp2	NP_995788.1	Peptidase_M10	143..301	CDD:278824	65/160 (41%)
		ZnMc_MMP	143..301	CDD:239805	65/160 (41%)
		HX	513..707	CDD:238046	66/205 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	97	1.000	Domainoid score	I2423
eggNOG	1	0.900	-	-		E1_KOG1565
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	232	1.000	Inparanoid score	I2171
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm995
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10201
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3504
SonicParanoid	1	1.000	-	-		X44
	9	9.000