Protein Alignment Mmp1 and Mmp19

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001100629.1
• Gene: Mmp19 / 304608
• RGDID: 1311376
• Length: 517
• Species: Rattus norvegicus
• Alignment Length: 510
• Identity: 187/510 - (36%)
• Similarity: 263/510 - (51%)
• Gaps: 62/510 - (12%)

  Fly    36 YLSQFGYLPASARNPASSGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDRVG 100
            ||.|:|||...........|.|   ...|:..||..:.|.::|::|..|...|..||||:.|..
  Rat    32 YLLQYGYLQKPLEGADDFRLED---ITEALRTFQEASELPVSGQMDDATRARMKQPRCGLEDPF- 92

  Fly   101 TGDSRSKRYALQGSRWRVKNLTYKISKYPKRLKRVDVDAEIGRAFAVWSEDTDLTFTRKTSGPVH 165
              :.::.:|.|.| .||.|:||::|...|..|....|.|.:.:||..||....|||....:|...
  Rat    93 --NQKTLKYLLLG-HWRKKHLTFRILNVPSTLSPSRVRAALHQAFKYWSNVAPLTFREVKAGWAD 154

  Fly   166 IEIKFVESEHGD-----GDAFDGQGGTLAHAFFPVFGGDAHFDDAELWTIGSPRGTNLFQVAAHE 225
            |.:.|    ||.     .::|||.|..||||..|.. |..|||:.|.||.|:.:|.||..:||||
  Rat   155 IRLSF----HGRQSPYCSNSFDGPGKVLAHADVPEL-GSVHFDNDEFWTEGTYQGVNLRIIAAHE 214

  Fly   226 FGHSLGLSHSDQSSALMAPFYRGFEPVFKLDEDDKAAIQSLYGRKTNQLRP----------TNVY 280
            .||:|||.||..:.|||||.|.|::|.|:|..||.|.||:|||::    ||          .:..
  Rat   215 VGHALGLGHSRYTQALMAPVYAGYQPYFRLHPDDVAGIQALYGKR----RPEPEDEEEEVEMHTV 275

  Fly   281 PATTQRPYSPPKVPLDDSICKDSKVDTLFNSAQGETYAFKGDKYYKLTTDSVEEGYPQL--ISKG 343
            ...|.:| ||...|     | .|:||.:....:|:||||||| |....|||   |...|  :|..
  Rat   276 STVTTKP-SPMPNP-----C-SSEVDAMMLGPRGKTYAFKGD-YVWTVTDS---GPGPLFRVSAL 329

  Fly   344 WPGLPGNIDAA-FTYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIPDHLDAAMVWGGNG 407
            |.|||||:||| ::.:..:|:||||.:.|||...::...:|.:::.    :..:||||:.|..|.
  Rat   330 WEGLPGNLDAAVYSPRTQRTHFFKGNKVWRYVDFKLSPGFPMKLNR----VEPNLDAALYWPVNQ 390

  Fly   408 KIYFFKGSKFWRFDPAKRPPVKASYPKPISN-WEGVPNNLDAALKYTNGYTYFFKGDKYYRFH-D 470
            |::.||||.:|::|...|..: :.|||||.. :.|||:...||:.:.:|..|||||.:|:|.: .
  Rat   391 KVFLFKGSGYWQWDELTRTDL-SRYPKPIKELFTGVPDQPSAAMSWQDGQVYFFKGKEYWRLNQQ 454

  Fly   471 ARFAVDSATPPFPRPTAHWWFGCKNTP---SSTGNIVEGSDNEFEQHSMIPHADD 522
            .|.|     ..:||.|.||......||   |.||::.  :....|....:|.|.|
  Rat   455 LRVA-----KGYPRNTTHWMHCSPRTPDTNSLTGDVT--TPATVESVLDVPSATD 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223	15/51 (29%)
		Peptidase_M10	115..268	CDD:425668	69/157 (44%)
		HX	298..493	CDD:238046	76/199 (38%)
Mmp19	NP_001100629.1	PG_binding_1	27..81	CDD:460223	15/51 (29%)
		ZnMc_MMP	105..257	CDD:239805	69/156 (44%)
		HX	286..471	CDD:238046	77/204 (38%)