Protein Alignment Mmp1 and Prg4

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001099432.4
• Gene: Prg4 / 289104
• RGDID: 1308976
• Length: 1275
• Species: Rattus norvegicus
• Alignment Length: 289
• Identity: 77/289 - (26%)
• Similarity: 113/289 - (39%)
• Gaps: 80/289 - (27%)

  Fly   273 QLRP-TNVYPATTQRPYSPPKVPLDDSICKDSKVDTLFNSAQGETYAFKGDKYYKLTTDSVEEGY 336
            :|.| .|::|..:.          :.:||....||.|.....|...||:| .|:.:.........
  Rat   998 RLNPGINIHPMFSD----------ETNICNGKPVDGLTTLRNGTLVAFRG-HYFWMLNPFRPPSP 1051

  Fly   337 PQLISKGWPGLPGNIDAAFTYKN--GKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIPDHLDA 399
            |:.|::.| |:|..||..||..|  |||:|||.:||||:....||..|||.|.:||.|:...:.|
  Rat  1052 PRRITEVW-GIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDVMDAGYPKLIVKGFGGLTGKIVA 1115

  Fly   400 AM-----------VW----GGNGKIYFFKGS-----------------------KFWRFDPAKRP 426
            |:           |:    |||.:.|.:|..                       :..||:.|..|
  Rat  1116 ALSIAKYKDRPESVYFFKRGGNIQQYTYKQEPVRKCTGRQPAINYSVYGQAAQVRRRRFERAVGP 1180

  Fly   427 ------------PVKASYP---------KPISNWEGVPNNLDAALKYTN-----GYTYF-FKGDK 464
                        |:||||.         |..:.|.|.||.:.:|:...|     ||.|: |..|:
  Rat  1181 FQTHTFRIHYSVPIKASYQDKGFLHNEVKVSTLWRGFPNVVTSAITLPNIRKPDGYDYYAFSKDQ 1245

  Fly   465 YYRFHDARFAVDSATPPFPRPTAHWWFGC 493
            ||..........:.|....:..:..|:.|
  Rat  1246 YYNIDVPTRTARAITTRSGQTLSRVWYNC 1274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223
		Peptidase_M10	115..268	CDD:425668
		HX	298..493	CDD:238046	72/261 (28%)
Prg4	NP_001099432.4	SO	26..68	CDD:197571
		Somatomedin_B	69..106	CDD:460034
		PHA03247	<315..724	CDD:223021
		HX	1013..1274	CDD:238046	72/262 (27%)