DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mmp1 and W01F3.2

DIOPT Version :9

Sequence 1:	NP_726473.2	Gene:	Mmp1 / 37949	FlyBaseID:	FBgn0035049	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	NP_507992.1	Gene:	W01F3.2 / 180351	WormBaseID:	WBGene00012185	Length:	307	Species:	Caenorhabditis elegans

Alignment Length:	259	Identity:	55/259 - (21%)
Similarity:	95/259 - (36%)	Gaps:	78/259 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 LFQVAAH-------------------EFGHSLGLSHSDQ---SSALMAPFYRGFEPVFKLDEDDK 260
            |..||||                   ..|..:.:.|:|:   :..::.||.   :|.........
Worm     6 LLLVAAHVANGLFGFGEKKTTQAPKISLGSEISIPHTDEDQDTGEIVIPFN---DPSTTTTRRRT 67

  Fly   261 AA-----IQSLYG------RKTNQLR--PTNVYP---ATTQRPYSPPKVPLDD----SICKDSKV 305
            |.     :.|:.|      |.|..:|  .|.:.|   |.|:|      :|..|    |.| .:::
Worm    68 ATTTGIPVISVGGIGLDRTRSTVDVRSFTTTINPRFTAATKR------LPSSDRHSSSGC-PNRI 125

  Fly   306 DTLFNSAQGETYAFKGDKYYKLTTDSVEEGYPQLISKGWPGLPGNIDAA---------FTYKNGK 361
            |. :.......|||...:.:|::.:.:.: ...|:.:...| |..::.|         :......
Worm   126 DA-YTFGPDSDYAFYEQQVFKISNNRISD-RTTLVEEFKDG-PNQVNGALYDPEREILWLVDGRS 187

  Fly   362 TYFFK--GTQYWRYQGRQMDGVYPKEI--SEGFTGIPDHLDAAMVWGGNGKIYFFKGSKFWRFD 421
            .|.:|  |:..|:.|     .|:|||:  |.|||.     :||:.|....::....|.||..:|
Worm   188 VYGYKKDGSDNWKLQ-----SVFPKELPSSIGFTP-----EAAVRWHNKHQLLLSNGGKFALYD 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:279773
		Peptidase_M10	115..268	CDD:278824	13/76 (17%)
		ZnMc_MMP	115..268	CDD:239805	13/76 (17%)
		HX	298..493	CDD:238046	31/137 (23%)
W01F3.2	NP_507992.1	HX	122..299	CDD:295316	29/133 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000127
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10201
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010