DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mmp1 and Y50D7A.13

DIOPT Version :9

Sequence 1:	NP_726473.2	Gene:	Mmp1 / 37949	FlyBaseID:	FBgn0035049	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	NP_001299905.1	Gene:	Y50D7A.13 / 13188188	WormBaseID:	WBGene00194737	Length:	194	Species:	Caenorhabditis elegans

Alignment Length:	179	Identity:	49/179 - (27%)
Similarity:	77/179 - (43%)	Gaps:	34/179 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 RWRVKNLTYKISKYPKRLKRV----DVDAEIGRAFAVWS---------EDTDLTFTRKTSGPVHI 166
            ||..:.:|:..|. |.||...    .|...:..|.|.|:         |:..:.      ....|
Worm    26 RWSHRRITWSFSD-PFRLLTAHQFQGVRLTVQEAVARWAIALEGLVEFEEVPVV------DAADI 83

  Fly   167 EIKFVESEHGDGDAFDGQGGTLAHAFFPVFGGDAHFDDAELWTI-------GSPRGTNLFQVAAH 224
            .:.|.:..|...:.|||:||.:||:.:|.: |..|.|..|.|..       .:.:..:|..|..|
Worm    84 TVLFAKKNHSCYEEFDGKGGVVAHSMYPPY-GVLHLDGDEEWHTRRWEEDGEASKYIDLRLVLIH 147

  Fly   225 EFGHSLGLSHSDQSSALMAPFYRGFEPV----FKLDEDDKAAIQSLYGR 269
            |.||:|||.||.:.:::|...|.  :|.    .:|.:.|..||:.|||:
Worm   148 EIGHTLGLRHSRRKTSVMRKHYE--KPAKIGKIQLSKYDIRAIRKLYGQ 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:279773
		Peptidase_M10	115..268	CDD:278824	47/176 (27%)
		ZnMc_MMP	115..268	CDD:239805	47/176 (27%)
		HX	298..493	CDD:238046
Y50D7A.13	NP_001299905.1	ZnMc_MMP	26..193	CDD:239805	47/176 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101521
Panther	1	1.100	-	-	O	PTHR10201
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910