Protein Alignment Mmp1 and Mmp1

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_308849.4
• Gene: Mmp1 / 1270173
• VectorBaseID: AGAMI1_001178
• Length: 568
• Species: Anopheles gambiae
• Alignment Length: 579
• Identity: 383/579 - (66%)
• Similarity: 444/579 - (76%)
• Gaps: 34/579 - (5%)

  Fly    10 IVVGTLFSIMAAAQSAPVSTTTQAEIYLSQFGYLPASARNPASSGLHDQRTWVSAIEEFQSFAGL 74
            ::||.    .||..::|||||.|||:||||||||....|||.|..|.||.||..||.||||||||
Mosquito    15 VLVGA----CAAGTASPVSTTPQAELYLSQFGYLSPKYRNPTSGNLLDQDTWEKAIMEFQSFAGL 75

  Fly    75 NITGELDAETMKLMSLPRCGVRDRVGTG-DSRSKRYALQGSRWRVKNLTYKISKYPKRLKRVDVD 138
            |:|||||.|||:|||||||||:|:||.| |:||||||||||||:||:|||:|||||:||:|..||
Mosquito    76 NVTGELDGETMQLMSLPRCGVKDKVGFGSDTRSKRYALQGSRWKVKDLTYRISKYPRRLERTAVD 140

  Fly   139 AEIGRAFAVWSEDTDLTFTRKTSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFPVFGGDAHFD 203
            .||.:||.||||.|||.||.|.:|.|||:|:|.|:||||||.|||.|||||||:|||:|||||||
Mosquito   141 KEIAKAFGVWSEYTDLRFTPKKTGAVHIDIRFEENEHGDGDPFDGPGGTLAHAYFPVYGGDAHFD 205

  Fly   204 DAELWTIGSPRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEPVFKLDEDDKAAIQSLYG 268
            |||.|||..||||||||||||||||||||||||..||||||||||::|||:||.||...||:|||
Mosquito   206 DAEQWTIDKPRGTNLFQVAAHEFGHSLGLSHSDVRSALMAPFYRGYDPVFRLDSDDIQGIQTLYG 270

  Fly   269 RKT-NQLRPTNVYPATTQRPYSPPKVPLDDSICKDSKVDTLFNSAQGETYAFKGDKYYKLTTDSV 332
            .|| |........|..|.||.:|.:  :|..:|...|:|.:||:|.|.|||||||||||||.::|
Mosquito   271 TKTRNPGGGAGATPTRTPRPKTPTE--MDSELCTSPKIDAIFNTADGSTYAFKGDKYYKLTENAV 333

  Fly   333 EEGYPQLISKGWPGLPGNIDAAFTYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIPDHL 397
            .||||:.||.|||||||||||||||||||||||:||:|||||||.:||.|||||||||||:||||
Mosquito   334 AEGYPKKISDGWPGLPGNIDAAFTYKNGKTYFFQGTKYWRYQGRTIDGDYPKEISEGFTGVPDHL 398

  Fly   398 DAAMVWGGNGKIYFFKGSKFWRFDPAKRPPVKASYPKPISNWEGVPNNLDAALKYTNGYTYFFKG 462
            ||||||||||||||:||||||||||.||||||::|||||||||||||::||||:||||||||||.
Mosquito   399 DAAMVWGGNGKIYFYKGSKFWRFDPLKRPPVKSTYPKPISNWEGVPNSVDAALQYTNGYTYFFKD 463

  Fly   463 DKYYRFHDARFAVDSATPPFPRPTAHWWFGCKNTPS---STGNI-VEGSDNEFEQHSMIPHADDG 523
            ||||||:|..|.||.:.|||||||||||:|||||||   :.||: ::.||.         |..|.
Mosquito   464 DKYYRFNDRTFTVDQSDPPFPRPTAHWWYGCKNTPSTFNTLGNVRLQKSDE---------HPYDI 519

  Fly   524 NGDDFDAAVGDHQSNDEPIVPEVAERTGNGAMSQSKLTSSSAVSTVITTILM--CLVSK 580
            .....|||..|.|       |:....:||||   |.:||.| ::|.:...|:  .|||:
Mosquito   520 GDLAQDAADTDDQ-------PDPDGYSGNGA---STITSVS-ITTALAGFLLGAYLVSR 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223	39/55 (71%)
		Peptidase_M10	115..268	CDD:425668	114/152 (75%)
		HX	298..493	CDD:238046	154/194 (79%)
Mmp1	XP_308849.4	None