Protein Alignment Mmp1 and Mmp28

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001307229.1
• Gene: Mmp28 / 118453
• MGIID: 2153062
• Length: 520
• Species: Mus musculus
• Alignment Length: 509
• Identity: 180/509 - (35%)
• Similarity: 260/509 - (51%)
• Gaps: 70/509 - (13%)

  Fly    32 QAEIYLSQFGYL-PASARNPASSGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGV 95
            :||.:|.::||| ...::.|||:...      :||.|||..:.|.::|.||..|::.|:.|||||
Mouse    35 EAEAFLEKYGYLSEQGSKAPASAQFR------NAIREFQWISQLPLSGVLDQATLRQMTRPRCGV 93

  Fly    96 RD---------RVGT---GD----SRSKRYALQGSRWRVKNLTYKISKYPKRLKRVDVDAEIGRA 144
            .|         |:.|   |.    .|.||:|..|::|..::|:|::..:|:||....|...:..|
Mouse    94 ADTDSHATWTERISTLLAGHRAKMRRKKRFAKPGNKWYKQHLSYRLVNWPERLPEPAVRGAVRAA 158

  Fly   145 FAVWSEDTDLTF-TRKTSGPVHIEIKFVESEHGDG--DAFDGQGGTLAHAFFPVFGGDAHFDDAE 206
            |.:||..:.|.| ....:||..|.:.|.:.:|.||  :||||.||.|||||.| ..|:||||..|
Mouse   159 FQLWSNVSALEFWEAPATGPADIRLTFFQGDHNDGLANAFDGPGGALAHAFLP-RRGEAHFDGDE 222

  Fly   207 LWTIGSPRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEPVFKLDEDDKAAIQSLYGRK- 270
            .|::...||.|||.|.|||.||:|||:||....|||||:|:.......|..||..|:|||||:.
Mouse   223 RWSLSRRRGRNLFVVLAHEIGHTLGLTHSPAPRALMAPYYKKLGRDALLSWDDVLAVQSLYGKPL 287

  Fly   271 ----TNQLRPTNVY-------PATTQ--RPYS-PPKVPLDDSICKDSKVDTLFNSAQGETYAFKG 321
                ..|| |..|:       |..:|  ||.: .||      .| .|..|.:....|...|.|||
Mouse   288 GRSVATQL-PGKVFTDFEAWDPHNSQSRRPETRGPK------YC-HSSFDAITVDGQWRLYVFKG 344

  Fly   322 DKYYKLTTD-SVEEGYPQLISKGWPGLPGNID-AAFTYKNGKTYFFKGTQYWRYQGRQMDGVYPK 384
            ..::::|.| :|.|  |:.:.|.|||||..|: ||.:.::|..|||||.:.||:||.:....:.:
Mouse   345 SYFWEVTVDGNVSE--PRPLQKRWPGLPPGIEAAAVSLEDGDFYFFKGNRCWRFQGTKSVWGFAQ 407

  Fly   385 EISEGFTGIPDHLDAAMVWGGNGKIYFFKGSKFWRFDPAKRPPVKASYPKPISNWEGVPNNLDAA 449
            ....|  |:|.|.|||:.:....::..||||:::....... .|:..||:.:.:|.|||..:..|
Mouse   408 LCRAG--GLPRHPDAALFFPPLRRLVLFKGSRYYVLAQGGM-QVEPYYPRSLRDWAGVPEEVSGA 469

  Fly   450 LKYTNGYTYFFKGDKYYRFHDARFAVDSATPPFPRPTAHW-----WFGCKNTPS 498
            |...:|...||:.|.|:....|:..|.|        :..|     |.||.|..|
Mouse   470 LPRPDGSIIFFRDDHYWHLDQAKLRVTS--------SGRWATELSWMGCWNANS 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223	19/56 (34%)
		Peptidase_M10	115..268	CDD:425668	68/155 (44%)
		HX	298..493	CDD:238046	62/201 (31%)
Mmp28	NP_001307229.1	PG_binding_1	31..86	CDD:460223	19/56 (34%)
		ZnMc_MMP	129..284	CDD:239805	68/155 (44%)
		HX	321..510	CDD:238046	64/208 (31%)